1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G 蛋白化合物库 - GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF SDF

G 蛋白偶连受体 (GPCR) 是人类基因组中最大的一类膜蛋白,参与多种信号转导过程。信号分子与GPCR 结合,导致 G 蛋白的激活,并参与下一步的信号传递过程。GPCR 受体在机体内发挥着特别重要的作用,对这些受体的进一步认识也会对现代医学产生一定的影响。事实上,研究人员预计,将有三分之一至一半数量的上市药物都是靶向 GPCR 受体的。GPCR 受体是药物开发中的一类主要靶点。

MCE 收录了 1798 种靶向 GPCRs 的小分子化合物,可以用于 GPCR 相关的不同研究及药物开发筛选。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE GPCR/G 蛋白化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1764 个产品以 10 mM 浓度提供,34 个产品以 2 mM 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
规格 (Pre-dissolved Solution or Solid) 价格 是否有货
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

立刻询价 In-stock
50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

立刻询价 In-stock
100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

立刻询价 In-stock
2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

立刻询价 In-stock

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  • 生物活性

  • 产品详情

  • 化合物库组成

  • 产品资料

活性描述 & 特点

•   A unique collection of 1798 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

产品详情
Formulation:
A collection of 1798 GPCR/G Protein related compounds supplied as pre-dissolved Solutions or Solid
Solution: 1764 compounds supplied in 10 mM solution, 34 compounds supplied in 2 mM solution.
Layout:
96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
化合物库组成

GPCR/G Protein Compound Library

Source: MedChem Express

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    产品名称:
    GPCR/G Protein Compound Library
    目录号:
    HY-L006
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack