2. Cell Cycle/DNA Damage Apoptosis
  3. DNA/RNA Synthesis Apoptosis
  4. 2,4-D sodium salt

2,4-D sodium salt  (Synonyms: Sodium 2,4-dichlorophenoxyacetate; 2,4-Dichlorophenoxyacetic acid sodium salt)

目录号: HY-18572A
COA 产品使用指南

摩尔计算器

2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) 是一种具有口服活性的用于阔叶杂草防治的选择性除草剂。2,4-D sodium salt 可诱导细胞凋亡 (apoptosis)。2,4-D sodium salt 抑制 DNA 和蛋白质的合成，从而阻止植物的正常生长发育。

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2,4-D sodium salt Chemical Structure

2,4-D sodium salt Chemical Structure

CAS No. : 2702-72-9

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500 mg ￥350
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1 g ￥550
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Other Forms of 2,4-D sodium salt:

2,4-D sodium salt 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D sodium salt can induce < b>apoptosis. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].

体外研究
(In Vitro)

2,4-D sodium salt (25-200 μM, 72 h) 抑制 A549 和 WI38 的细胞活力，IC50 值分别为 126 ± 2.25 µM 和 115 ± 4.39 µM。通过影响细胞周期，诱导细胞凋亡[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2,4-D sodium salt 相关抗体:

Cell Viability Assay[2]

Cell Line: A549, W138
Concentration: 25, 50, 75, 100, 150, 200 μM
Incubation Time: 72 h
Result: Inhibited cell viability in a dose-dependent manner.

Cell Cytotoxicity Assay[2]

Cell Line: A549
Concentration: 50, 100, 150 μM
Incubation Time: 72 h
Result: The G0/G1 population decreased to about 57%, 43% and 31%, respectively.

Apoptosis Analysis[2]

Cell Line: A549, W138
Concentration: 100, 150 μM
Incubation Time: 72 h
Result: The early apoptotic population increased to 44% in A549 cells and 57% in WI38 cells, and the late apoptotic population increased to 18% in A549 cells and 10% in WI38 cells.

Western Blot Analysis[2]

Cell Line: A549, W138
Concentration: 100, 150 μM
Incubation Time: 72 h
Result: Up-regulated p53 and Bax proteins, down-regulated Bcl-2 and pro caspase 3.
体内研究
(In Vivo)

2,4-D sodium salt (100 或 200 mg/kg, 灌胃, 连续30 天) 对雄性大鼠生殖系统有毒性作用[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult Wistar male rats[3]
Dosage: 100 or 200 mg/kg
Administration: i.g.
Result: Decreased the testis , seminal vesicles and prostate relative weight.
Decreased the number of spermatozoa and sperm motility.
Increased the level of FSH and LH.
分子量

243.02

Formula

C8H5Cl2NaO3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥98.0%

COA (191 KB) HNMR (111 KB)

产品使用指南 (1538 KB)
参考文献

2,4-D sodium salt 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,4-D2702-72-9Sodium 2,4-dichlorophenoxyacetate2,4-Dichlorophenoxyacetic acidDNA/RNA SynthesisApoptosisA549W138HerbicideFSH， LHInhibitorinhibitorinhibit

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