1. Screening Libraries
  2. Cell Cycle/DNA Damage Compound Library

细胞周期/DNA 损伤化合物库 - Cell Cycle/DNA Damage Compound Library

Cat. No.: HY-L004
Library Contents: XLSX PDF SDF

DNA 容易受到多种形式的损伤,为了应对 DNA 损伤,细胞已经进化出一系列的修复机制。不断生长和增殖的细胞受到到 DNA 损伤的几率会更高。细胞周期检查点代表 DNA 修复的整体组成部分,通过协调细胞周期及其他生化途径,以应对损伤,恢复 DNA 结构。通过延迟细胞周期的进展,检查点在 DNA 复制的关键阶段 (基因组复制时) 和有丝分裂 (基因组分离时) 之前提供了更多的修复时间。检查点功能的缺失或衰减可以通过降低 DNA 修复的效率而增加自发性和诱导性基因突变和染色体畸变。

MCE 收录 800 个细胞周期调控及 DNA 损伤及修复相关的化合物,可以用于细胞周期调控、DNA 损伤及修复相关的研究。

Cell Cycle/DNA Damage Compound Library
Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

Please contact us at

sales@MedChemExpress.cn

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Composition

  • Documentation

Description
& Advantages

•   A unique collection of 800 Cell Cycle/DNA Damage related compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.

•   A useful tool to study the mechanism of cell cycle regulators that are critical to normal development and the development of cancer, cardiovascular, inflammatory, and neurodegenerative diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 800 Cell Cycle/DNA Damage related compounds supplied as pre-dissolved DMSO solutions or Solid
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Cell Cycle/DNA Damage Compound Library

Source: MedChem Express

Contents of Cell Cycle/DNA Damage Compound Library
Documentation

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Cell Cycle/DNA Damage Compound Library
目录号:
HY-L004
需求量:

Request SDF File

Please enter your email address. We will send your requested SDF file to you as soon as possible.