1. GPCR/G Protein Metabolic Enzyme/Protease
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  3. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 

目录号: HY-100287
产品使用指南

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 是一种由压力诱发的溃疡和低毒性抑制剂,可以在压力引起的溃疡大鼠中,维持磷脂酶 A2 (phospholipase A2) 和 前列腺素 E2 (prostaglandin E2) 的含量水平。

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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Chemical Structure

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Chemical Structure

CAS No. : 137089-36-2

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生物活性

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

IC50 & Target

PGI2

 

PLA2

 

体内研究
(In Vivo)

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

339.58

Formula

C20H37NOS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
目录号:
HY-100287
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