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  3. RPH-2823

RPH-2823,是一种基本的氨苯二烯衍生物,能引起短路电流 (SCC) 的剂量依赖性降低和跨上皮电阻的增加。

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RPH-2823 Chemical Structure

RPH-2823 Chemical Structure

CAS No. : 96558-24-6

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance[1].

体外研究
(In Vitro)

RPH-2823 influences transepithelial Na+ transport by interacting with the Na+ channel or a regulator site of it within the apical membrane[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

RPH 2823 (2.5 mumol/kg) can avoid the kaliuresis of 25 mumol/kg furosemide in male Wistar rats. RPH 2823 (1 mg/kg and 5 mg/kg, i.v.) has a terminal elimination half-life of 3 h. About 47% of the given dose are excreted unchanged with urine[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

370.41

Formula

C17H22N8O2

CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

RPH-2823 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RPH-2823
目录号:
HY-101595
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