1. 点击化学
  2. 叠氮化物
  3. UAA crosslinker 1

UAA crosslinker 1 

目录号: HY-111434 纯度: ≥97.0%
COA 产品使用指南

UAA crosslinker 1 hydrochloride 是一种用于非标准氨基酸 (ncAAs) 掺入的琥珀色密码子。ncAAs 可利用某些野生型和工程氨基酰-tRNA 合成酶的混杂活性在体内合成蛋白质。UAA crosslinker 1 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。它还可以和含有 DBCOBCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。

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UAA crosslinker 1 Chemical Structure

UAA crosslinker 1 Chemical Structure

CAS No. : 1167421-25-1

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规格 价格 是否有货 数量
5 mg ¥690
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10 mg ¥1100
In-stock
25 mg ¥2200
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Other Forms of UAA crosslinker 1:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1]. UAA crosslinker 1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

分子量

259.26

Formula

C9H17N5O4

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥97.0%

参考文献

UAA crosslinker 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
UAA crosslinker 1
目录号:
HY-111434
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