1. GPCR/G Protein
  2. Adenosine Receptor
  3. Adenosine A1 receptor activator T62

Adenosine A1 receptor activator T62 

目录号: HY-106199 纯度: 98.93%
COA 产品使用指南

Adenosine A1 receptor activator T62 是腺苷 A1 受体 (adenosine A1 receptor) 的变构增强剂。Adenosine A1 receptor activator T62 在急性疼痛的动物模型中产生抗伤害感受,并在炎性和神经损伤性疼痛的模型中降低超敏反应。

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Adenosine A1 receptor activator T62 Chemical Structure

Adenosine A1 receptor activator T62 Chemical Structure

CAS No. : 40312-34-3

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor. Adenosine A1 receptor activator T62 produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].

IC50 & Target

Adenosine A1 receptor[1]

体内研究
(In Vivo)

Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male SpragueDawley rats (250 g) after paw incision surgery[1]
Dosage: 0.3 μg, 0.5 μg, 1 μg, and 3 μg
Administration: Intrathecal administration
Result: Produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) was 0.77 (0.63-0.91) μg.
Clinical Trial
分子量

291.80

Formula

C15H14ClNOS

CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 98.93%

参考文献

Adenosine A1 receptor activator T62 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Adenosine A1 receptor activator T62
目录号:
HY-106199
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