2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor mAChR
  4. ADS1017

ADS1017 是组胺受体 (histamine receptor) 和毒蕈碱受体 (muscarinic receptor) 的拮抗剂，对 hH3R、hH4R、hM2R 和 hM4R 具有良好的亲和力，pKi 分别为 6.8、5.5、7.4 和 7.2。ADS1017 在 Capsaicin (HY-10448) 或 Oxaliplatin (HY-17371) 诱发的小鼠疼痛模型中表现出镇痛和抗痛觉过敏作用。

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ADS1017

ADS1017 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

ADS1017 相关抗体

Top Publications Citing Use of Products

查看 Histamine Receptor 亚型特异性产品:

查看所有亚型
H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

查看 mAChR 亚型特异性产品:

查看所有亚型
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ADS1017 is the antagonist for histamine receptor and muscarinic receptor, that exhibits good affinities to hH3R, hH4R, hM2R and hM4R with pKi of 6.8, 5.5, 7.4 and 7.2. ADS1017 exhibits analgesic and anti-allodynic efficacy in mice Capsaicin (HY-10448)-or Oxaliplatin (HY-17371)-induced pain models[1].

分子量

479.70

Formula

C29H45N5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ADS1017 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ADS1017ADS 1017ADS-1017Histamine ReceptormAChRMuscarinic acetylcholine receptorantiallodynicantinociceptiveantihyperalgesicInhibitorinhibitorinhibit

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产品名称：
ADS1017
目录号：
HY-170444
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