2. Immunology/Inflammation
  3. COX
  4. Anti-inflammatory agent 56

Anti-inflammatory agent 56 (Compound 9) 是一种选择性的 COX-2 抑制剂 (IC50: 0.54 μM)。Anti-inflammatory agent 56 具有抗氧化和抗炎作用。Anti-inflammatory agent 56 抑制氧化应激诱导的细胞死亡。Anti-inflammatory agent 56 通过抑制 Keap1、COX-2 和 iNOS 来抑制氧化应激和神经炎症。Anti-inflammatory agent 56 对小鼠的急性毒性较低(LD50: 1000 mg/kg)。

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Anti-inflammatory agent 56 Chemical Structure

Anti-inflammatory agent 56 Chemical Structure

CAS No. : 2413127-32-7

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Anti-inflammatory agent 56 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

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COX COX-1 COX-2 COX-3

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生物活性

Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD50: 1000 mg/kg)[1].

IC50 & Target

COX-2

 

分子量

476.43

Formula

C21H15F3N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-inflammatory agent 56 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 562413127-32-7COXCyclooxygenaseanti-inflammatoryMCAO modelAcute ischemic strokeLPSInhibitorinhibitorinhibit

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产品名称：
Anti-inflammatory agent 56
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HY-155997
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