1. Anti-infection
  2. Influenza Virus
  3. Anti-Influenza agent 3

Anti-Influenza agent 3 (compound 11h) 是一种有效的 anti-influenza 药剂对 A/HK/68 (H3N2, M2-WT) 和 A/WSN/33 (H1N1, M2-S31N) 菌株的 EC50 值分别为 3.29 和 2.45 µM。Anti-Influenza agent 3 对 MDCK 上皮细胞具有低细胞毒性。Anti-Influenza agent 3 抑制 M2 WT 和 S31N 离子通道电导率。

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Anti-Influenza agent 3 Chemical Structure

Anti-Influenza agent 3 Chemical Structure

CAS No. : 2481321-20-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with EC50 values of 3.29, 2.45 µM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity[1].

IC50 & Target

EC50: 3.29 µM (H3N2); 2.45 µM (H1N1)[1].

体外研究
(In Vitro)

Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µM[1].
Anti-Influenza agent 3 (100 µM) inhibits the M2 WT and S31N ion channel conductivity in 293 T-Rex cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

311.87

Formula

C16H22ClNOS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anti-Influenza agent 3 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anti-Influenza agent 3
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