2. Anti-infection
  3. Bacterial
  4. Anti-MRSA agent 4

Anti-MRSA agent 4 (compound 7a) 是革兰氏阳性耐甲氧西林金黄色葡萄球菌 (MRSA)的强效选择性生长抑制剂，MIC ≤ 0.26 µM。Anti-MRSA agent 4 在 HEK293 细胞中未表现出细胞毒性和溶血活性。

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Anti-MRSA agent 4

Anti-MRSA agent 4 Chemical Structure

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Anti-MRSA agent 4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-MRSA agent 4 (compound 7a) is a potent and selective growth inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA), with MIC ≤ 0.26 µM. Anti-MRSA agent 4 exhibits no cytotoxic and no hemolytic activity in HEK293 cells[1].

IC50 & Target

MIC: ≤ 0.26 µM (MRSA)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 IC50
> 33.9 μM
Compound: 7a
Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 20 hrs by resazurin dye based assay
Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 20 hrs by resazurin dye based assay
[PMID: 35477062]
分子量

943.07

Formula

C48H68F6N4O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-MRSA agent 4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-MRSA agent 4BacterialS. aureusMRSAMethicillin-resistantGram-positiveAntibacterialHEK293Inhibitorinhibitorinhibit

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