2. Anti-infection Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Bacterial Reactive Oxygen Species (ROS)
  4. Anti-MRSA agent 40

Anti-MRSA agent 40 (Compound 7-8) 是一种强效的抗耐 Methicilin (HY-121544) 金黄色葡萄球菌 (MRSA) 剂。Anti-MRSA agent 40 对 MRSA2、S. aureus ATCC 29213 具有显著的抗菌活性，其 MIC 值均为 1 μg/mL。Anti-MRSA agent 40 能引起细胞膜去极化，损害膜完整性，同时升高 MRSA2 内 ROS 水平，最终导致细胞裂解和死亡。Anti-MRSA agent 40 的细胞毒性极低，且在有效抗菌浓度下几乎没有溶血风险。Anti-MRSA agent 40 在 MRSA2 皮肤脓肿模型中具有显著的疗效。Anti-MRSA agent 40 可用于研究抗 MRSA 感染。

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Anti-MRSA agent 40

Anti-MRSA agent 40 Chemical Structure

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Anti-MRSA agent 40 相关抗体

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  • 生物活性

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生物活性

Anti-MRSA agent 40 (Compound 7-8) is a potent agent against Methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 40 exhibits significant antibacterial activity against MRSA2 and S. aureus ATCC 29213, with its MIC values being 1 μg/mL. Anti-MRSA agent 40 causes depolarization of the cell membrane, damages membrane integrity, and simultaneously increases the level of ROS within MRSA2, ultimately leading to cell lysis and death. Anti-MRSA agent 40 exhibits extremely low cytotoxicity, and there is almost no risk of hemolysis at the effective antibacterial concentration. Anti-MRSA agent 40 shows significant efficacy in the MRSA2 skin abscess model. Anti-MRSA agent 40 can be used for research on anti-MRSA infections[1].

分子量

640.68

Formula

C36H36N2O9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-MRSA agent 40 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-MRSA agent 40BacterialReactive Oxygen Species (ROS)α-MangostinacylhydrazoneMRSAantibacterialsynergistic effectInhibitorinhibitorinhibit

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