2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 272

Antibacterial agent 272 (Compound Z22) 是一种以 DNA 及 DNA-拓扑异构酶 II (DNA - Topo II) 复合物为靶点的潜在抗菌剂。Antibacterial agent 272 对 Staphylococcus aureus 25923 和 29213 的 MIC 为 1 μg/mL，对 Staphylococcus epidermidis 12228 为 2 μg/mL，对 Enterococcus faecalis 为 2 - 4 μg/mL，对 Pseudomonas aeruginosa 9027 和 27853 为 4 μg/mL，展现出较强的抗菌活性。Antibacterial agent 272 通过与 DNA 碱基对嵌入结合，干扰细菌 DNA 的正常功能。Antibacterial agent 272 可用细菌感染疾病的研究。

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Antibacterial agent 272 Chemical Structure

Antibacterial agent 272 Chemical Structure

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Antibacterial agent 272 相关抗体

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  • 生物活性

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生物活性

Antibacterial agent 272 (Compound Z22) is a potential antimicrobial agent targeting DNA and the DNA-topoisomerase II (DNA-Topo II) complex, exhibiting MIC values of 1 μg/mL against Staphylococcus aureus 25923 and 29213, 2 μg/mL against Staphylococcus epidermidis 12228, 2-4 μg/mL against Enterococcus faecalis, and 4 μg/mL against Pseudomonas aeruginosa 9027 and 27853, demonstrating potent antibacterial activity. This compound functions by intercalating with DNA base pairs to disrupt normal bacterial DNA function, making it suitable for research on bacterial infectious diseases[1].

分子量

1053.33

Formula

C57H88N4O14
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 272 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 272Antibacterial agent272Antibacterial agent-272BacterialInhibitorinhibitorinhibit

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