1. Anti-infection
  2. Bacterial
  3. Antibiofilm agent-9

Antibiofilm agent-9 (Compound 4) 是一种具有抗菌活性的吡咯霉素衍生物。Antibiofilm agent-9 抑制 Bacillus anthracisMIC 为 0.031 μg/mL。Antibiofilm agent-9 表现出抗生物膜活性,生物膜抑制率为 84% (24 小时,8.0 μg/mL)。Antibiofilm agent-9 在小鼠模型中表现出良好的药代动力学特征。

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Antibiofilm agent-9

Antibiofilm agent-9 Chemical Structure

CAS No. : 2001602-07-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibiofilm agent-9 (Compound 4) is a pyrrolomycin derivative with antibacterial activity. Antibiofilm agent-9 inhibits Bacillus anthracis with MIC of 0.031 μg/mL. Antibiofilm agent-9 exhibits antibiofilm activity with 84% biofilm inhibition (24 h, 8.0 μg/mL). Antibiofilm agent-9 exhibits a good pharmacokinetic characters in mouse model[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
> 35.3 μM
Compound: 4
Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 24 hrs by MTS assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 24 hrs by MTS assay
[PMID: 27565555]
分子量

352.97

Formula

C11H5BrCl2FNO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antibiofilm agent-9 相关分类

  • 摩尔计算器

  • 稀释计算器

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质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antibiofilm agent-9
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HY-164123
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