2. 抗体
  3. 一抗
  4. 单克隆抗体 重组抗体
  5. POMC 抗体 (YA1619)

POMC 抗体 (YA1619)

目录号: HY-P81874
COA 抗体使用指南 技术支持

POMC Antibody (YA1619) 是一个兔来源、无偶联标记、抗 POMC 的 IgG 单克隆抗体。

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规格 价格 是否有货 数量
10 μL ￥470 In-stock
50 μL ￥1220 In-stock
100 μL ￥2000 In-stock
250 μL   询价  

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Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

POMC Antibody (YA1619) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POMC.
研究背景

The related gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidorelated genesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in The related gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
基因 ID
蛋白数据库
中文名
POMC 抗体 (YA1619)
同用名
Pro-opiomelanocortin; POMC; Corticotropin-lipotropin; NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone; ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin
分子量

Predicted band size: 29 kDa; Observed band size: 29 kDa
纯度

Affinity Chromatography
偶联

Non-conjugated
修饰

Unmodified
RRID
研究领域

Neuroscience
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Recombinant, Monoclonal
宿主

Rabbit
反应物种

Human, Mouse, Rat
推荐稀释比例

WB: 1:500-1:1000; IHC: 1:50-1:100; IP: 1:50
应用

WB, IHC-P, IP
性状

液体
组分

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
敏感性

Endogenous
免疫原

A synthesized peptide derived from human POMC
数据库

Entrez Gene: 5443 Human ; 18976 Mouse ;

SwissProt: P01189 Human ; P01193 Mouse ; P01194 Rat

OMIM: 601665 Human

文件资料

COA (194 KB)

抗体使用指南 (1083 KB)

POMC Antibody (YA1619) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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POMC Antibody (YA1619)
目录号：
HY-P81874
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