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  4. Anticancer agent 89

Anticancer agent 89 是一种具有抗肿瘤活性的苯并噻唑-2-噻吩 S-糖苷衍生物，对卵巢癌 (OVCAR-4)，肾癌 (A498) 和黑色素瘤 (SK-MEL-5) 细胞系有较高的抑制作用。

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Anticancer agent 89 Chemical Structure

Anticancer agent 89 Chemical Structure

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Anticancer agent 89 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5)[1].

体外研究
(In Vitro)

Anticancer agent 89 (compound 6f) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against three cell lines, SK-MEL-5, OVCAR-4, and A498[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 89 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration: 0-200 μg/mL
Incubation Time: 24 hours
Result: Showed nontoxic under the doses of 90 μg/mL (FRHK-4), 90 μg/mL (Hep2), μg/mL (BGM), 90 μg/mL (Vero), and 100 μg/mL (Huh 7.5), respectively.

Cell Viability Assay[1]

Cell Line: SK-MEL-5, OVCAR-4, and A498
Concentration: 0.01 mM
Incubation Time: 24 hours
Result: Inhibited SK-MEL-5, OVCAR-4, and A498 cell viability by 36.29%, 46.89%, and 36.08%, respectively.
分子量

777.68

Formula

C32H29BrN2O10S3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 89 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 89Anticancer agent89Anticancer agent-89OthersA498benzothiazole-2-thiophene S-glycosideantitumor activityrenal cancer cell lineInhibitorinhibitorinhibit

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目录号：
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