2. Cytoskeleton
  3. Collagen
  4. Antifibrotic agent 2

Antifibrotic agent 2 (Compound 636) 是一种具有抗纤维化活性的多环吡啶酮衍生物。Antifibrotic agent 2 通过调节成纤维细胞的异常增殖与活化，减少纤维连接蛋白、胶原蛋白 (collagen) 等纤维化相关蛋白的病理性积累，阻断过量纤维结缔组织在器官或组织中的沉积，逆转或延缓组织纤维化重塑。Antifibrotic agent 2 可用于肺纤维化的研究。

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Antifibrotic agent 2

Antifibrotic agent 2 Chemical Structure

CAS No. : 1590409-23-6

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Antifibrotic agent 2 相关抗体

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  • 生物活性

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生物活性

Antifibrotic agent 2 (Compound 636) is a polycyclic pyridinone derivative with antifibrotic activity. Antifibrotic agent 2 reduces the pathological accumulation of fibrosis-related proteins such as fibronectin and collagen, prevents excessive fibrous connective tissue from depositing in organs or tissues, and reverses or delays the remodeling of tissue fibrosisby regulating the abnormal proliferation and activation of fibroblasts. Antifibrotic agent 2 can be used for research on pulmonary fibrosis[1].

分子量

403.36

Formula

C19H16F3N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifibrotic agent 2 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifibrotic agent 21590409-23-6Antifibrotic agent2Antifibrotic agent-2CollagenAntifibroticfibrosis-related proteinsfibronectincollagenInhibitorinhibitorinhibit

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