2. Inhibitory Antibodies
  3. Atibuclimab

Atibuclimab 

目录号: HY-P99008 纯度: 97.74%
COA

摩尔计算器

Atibuclimab 是一种针对 CD14 的嵌合单克隆抗体，由小鼠可变区和人类 IgG4 Fc 区组成。Atibuclimab 可用于肌萎缩侧索硬化症的研究。Atibuclimab 可减轻 LPS 诱导的症状，并强烈抑制 LPS 诱导的促炎细胞因子释放，同时仅延迟抗炎细胞因子可溶性 TNF 受体 I 型和 IL-1 受体拮抗剂的释放。

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Atibuclimab Chemical Structure

Atibuclimab Chemical Structure

CAS No. : 2417175-94-9

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规格 价格 是否有货 数量
1 mg ￥2550
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5 mg ￥6600
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Atibuclimab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis[1]. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist[2].

CAS 号
性状

液体

颜色

Colorless to light yellow

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储存方式

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纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atibuclimab2417175-94-9OthersCD14amyotrophic lateral sclerosisproinflammatory cytokine releaseInhibitorinhibitorinhibit

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