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  3. Biochemical Assay Reagents
  4. EGTA tetrasodium

EGTA tetrasodium 是一种特殊的钙离子螯合剂。EGTA tetrasodium 在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA tetrasodium 显著抑制炎性巨噬细胞的底物粘附能力。

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EGTA tetrasodium Chemical Structure

EGTA tetrasodium Chemical Structure

CAS No. : 13368-13-3

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EGTA tetrasodium 的其他形式现货产品:

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EGTA tetrasodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGTA tetrasodium is a specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2].

体外研究
(In Vitro)

EGTA tetrasodium, proposed as endodontic irrigant, decreases substrate adherence capacity of inflammatory macrophages in a time- and dose-dependent manner. The EGTA tetrasodium concentration that causes an IC50 is 202 mM. Chelators react with calcium ions in the hydroxyapatite crystals to produce a metallic chelate. Removal of calcium ions from the dentine makes the dentinal tissue softer, especially the hydroxyapatite-rich peritubular dentin and increases the diameter of exposed dentinal tubules[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

EGTA tetrasodium 相关抗体:
分子量

468.28

Formula

C14H20N2Na4O10
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EGTA tetrasodium 相关分类

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  • 稀释计算器

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Keywords:

EGTA tetrasodium13368-13-3Biochemical Assay ReagentscalciumionchelatorendodonticirrigantinflammatorymacrophagesInhibitorinhibitorinhibit

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