1. GPCR/G Protein
  2. CaSR
  3. Etelcalcetide

Etelcalcetide (Synonyms: AMG 416; KAI-4169)

目录号: HY-P1955
产品使用指南

Etelcalcetide (AMG 416) 是一种合成肽,有钙敏感受体 (CaSR) 活化剂的作用。Etelcalcetide 可有效降低接受血液透析的继发性甲状旁腺功能亢进患者的 甲状旁腺激素 (PTH) 浓度。

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Custom Peptide Synthesis

Etelcalcetide Chemical Structure

Etelcalcetide Chemical Structure

CAS No. : 1262780-97-1

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Description

Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

Molecular Weight

1048.25

Formula

C₃₈H₇₃N₂₁O₁₀S₂

CAS No.

1262780-97-1

Sequence

{Cys1'}-Ac-{d-Cys1}-{d-Ala}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Ala}-{d-Arg}-NH2 (Disulfide bridge: Cys1'-Cys1)

Sequence Shortening

C'-Ac-d-C-d-A-d-R-d-R-d-R-d-A-d-R-NH2 (Disulfide bridge: Cys1'-Cys1)

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Etelcalcetide
目录号:
HY-P1955
需求量:

Etelcalcetide

Cat. No.: HY-P1955