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  3. Biochemical Assay Reagents
  4. Florbenazine

Florbenazine (AV-133) 是一种靶向中枢神经系统单胺转运蛋白 VMAT2 诊断显像剂，其 F-18 标记的形式可用于 PET 扫描。[18F]Florbenazine 在小鼠体内的生物分布显示出较高的纹状体/小脑比值 (0.48)，可用于神经退行性疾病（包括路易体痴呆和帕金森病）的诊断研究。

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Florbenazine

Florbenazine Chemical Structure

CAS No. : 937245-42-6

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Florbenazine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Florbenazine (AV-133) is a diagnostic imaging agent targeting the central nervous system monoamine transporter VMAT2, and its F-18 labeled form can be used for PET scanning. The biodistribution of [18F]Florbenazine in mice shows a high striatum/cerebellum ratio (0.48), which can be used for the diagnostic research of neurodegenerative diseases (including dementia with Lewy bodies and Parkinson's disease)[1].

IC50 & Target

VMAT2[1]
Clinical Trial
分子量

365.48

Formula

C21H32FNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Florbenazine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Florbenazine937245-42-6AV-133AV133AV 133Biochemical Assay ReagentsInhibitorinhibitorinhibit

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