1. Gene
  2. Npy - neuropeptide Y Gene

Npy - neuropeptide Y Gene

种属: Mus musculus

同用名: 0710005A05Rik

基因 ID: 109648 | 基因类型: protein coding

关于 Npy

功能概要

This gene encodes a neuropeptide that plays a pivotal role in many physiological functions such as food intake, energy homeostasis, circadian rhythm, and cognition. The encoded protein precursor undergoes proteolytic processing to generate the biologically active peptide. Mice lacking the encoded protein exhibit mild seizures occasionally and become hyperphagic following food deprivation. A deficiency of the encoded protein partially prevents mice lacking Leptin from becoming obese. [provided by RefSeq, Oct 2015]

Npy 基因产物(1)

mRNA Protein Name
NM_023456.3 NP_075945.1 pro-neuropeptide Y preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor binding IDA
IDA: 通过直接分析推断
10698177 MGI
enables G protein-coupled receptor binding IGI
IGI: 通过遗传相互作用推断
9623984 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of blood pressure IDA
IDA: 通过直接分析推断
9623984 MGI
involved in synaptic signaling via neuropeptide EXP
EXP: 通过实验结果推断
22190627 MGI
involved in synaptic signaling via neuropeptide IDA
IDA: 通过直接分析推断
22190627 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
22190627 MGI
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
22190627 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
24582971 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pro-neuropeptide Y

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npy NCBI NCBI:4852