Ccr5 - C-C motif chemokine receptor 5 Gene

中文名称：CC 基序趋化因子受体 5

种属: Rattus norvegicus

同用名: Ckr5; Cmkbr5

关于 Ccr5

功能概要

该基因编码的蛋白可启动蛋白激酶结合活性。参与多个过程，包括神经系统发育；细胞因子产生的正调节；和对细菌的反应。位于细胞表面和内体。用于研究老年痴呆症；瘟疫;和视觉性癫痫。多种疾病的生物标志物，包括动脉疾病（多种）；糖尿病（多发性）；晚期肾脏疾病;睾丸炎;和葡萄膜炎（多发）。该基因的人类直系同源物与多种疾病有关，包括川崎病；西尼罗热；自身免疫性疾病（多种）；铍中毒；和结节病（多发）。与人 CCR5（CC 基序趋化因子受体 5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase binding activity. Involved in several processes, including nervous system development; positive regulation of cytokine production; and response to bacterium. Located in cell surface and endosome. Used to study Alzheimer's disease; plague; and visual epilepsy. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); end stage renal disease; orchitis; and uveitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif Chemokine Receptor 5). [provided by Alliance of Genome Resources, Apr 2022]