2. Gene
  3. Wdr5 - WD repeat domain 5 Gene

Wdr5 - WD repeat domain 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Big; Big-3; 2410008O07Rik

基因 ID: 140858 | 基因类型: protein coding

关于 Wdr5

功能概要

Predicted to enable methylated histone binding activity. Predicted to contribute to Histone Methyltransferase activity (H3-K4 specific). Acts upstream of or within histone H3-K4 methylation; positive regulation of gluconeogenesis; and skeletal system development. Located in nucleus. Part of ATAC complex. Is expressed in cerebral cortex; testis; and vault of skull. Orthologous to human WDR5 (WD repeat domain 5). [provided by Alliance of Genome Resources, Apr 2022]

Wdr5 基因产物(1)

mRNA Protein Name
NM_080848.2 NP_543124.1 WD repeat-containing protein 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K4 methyltransferase activity IMP
IMP: 通过突变表型推断
24051374 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19103755 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of gluconeogenesis IGI
IGI: 通过遗传相互作用推断
24051374 MGI
acts upstream of or within peptidyl-lysine methylation IMP
IMP: 通过突变表型推断
24051374 MGI
acts upstream of or within positive regulation of gluconeogenesis IGI
IGI: 通过遗传相互作用推断
24051374 MGI
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
19103755 MGI
involved in regulation of cell division IDA
IDA: 通过直接分析推断
20562830 MGI
involved in regulation of embryonic development IDA
IDA: 通过直接分析推断
19103755 MGI
acts upstream of or within skeletal system development IDA
IDA: 通过直接分析推断
11551928 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ATAC complex IDA
IDA: 通过直接分析推断
19936620 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
11551928 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15860628 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

WD repeat-containing protein 5

BMP2-induced 3-kb gene protein

WD repeat-containing protein BIG-3

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-16994 OICR-0547 Inhibitor 99.85% Phase 1
Pre-clinical Phase
生物活性分子 (28)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16993 OICR-9429 Inhibitor 99.71% 否
HY-19347 WDR5-0103 Antagonist 99.94% 否
HY-133121 WDR5-IN-1 Inhibitor 98.0% 否
HY-154949 WDR5-IN-6 Inhibitor 99.83% 否
HY-111753A WDR5-IN-4 TFA Inhibitor 98.04% 否
HY-153728 WM-586 Inhibitor 98.74% 否
HY-111753 WDR5-IN-4 Inhibitor 98.13% 否
HY-153331 DDO-2213 Inhibitor 98.84% 否
HY-162014 WDR5 degrader-1 Degrader 98.00% 否
HY-148817 WDR5-0102 Inhibitor 97.07% 否
HY-157332 WDR5-IN-7 Inhibitor / 否
HY-P10948A CS-VIP 8 hydrochloride Inhibitor 96.04% 否
HY-150403 XF067-68 Degrader 99.56% 否
HY-157659 WDR5-MLL1 antagonist 1 Antagonist 98.34% 否
HY-178752 Z88418521 Ligand / 否
HY-175754 C3TD078 Inhibitor / 否
HY-150400 XF056-132 free base Degrader / 否
HY-174255 WDR5-MYC-IN-2 Inhibitor / 否
HY-175802 HBI-2375 Inhibitor / 否
HY-169389 OICR41114 Degrader / 否
HY-172196 LH168 / 否
HY-168475 DD0-2363 Inhibitor / 否
HY-169415 DBL-6-13 Inhibitor / 否
HY-159993 MR44397 Inhibitor / 否
HY-161123 WDR5-IN-8 Inhibitor / 否
HY-P10948 CS-VIP 8 Inhibitor / 否
HY-150400A XF056-132 Degrader / 否
HY-168488 WDR5 ligand 2 Ligand / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wdr5 NCBI NCBI:11091
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