Fgf2 - fibroblast growth factor 2 Gene

种属: Mus musculus

同用名: Fgfb; bFGF; Fgf-2; Fgf2a

基因 ID: 14173 | 基因类型: protein coding

关于 Fgf2

功能概要

Enables growth factor activity. Involved in stem cell development. Acts upstream of or within several processes, including animal organ development; positive regulation of macromolecule metabolic process; and positive regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (Fibroblast Growth Factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Fgf2 基因产物(1)

mRNA	Protein	Name
NM_008006.2	NP_032032.1	fibroblast growth factor 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables growth factor activity	IDA IDA: 通过直接分析推断	15608665	MGI
enables protein binding	IPI IPI: 通过物理相互作用推断	8393815	MGI

生物过程 GO 注释	逻辑证据	参考文献	来源
acts upstream of ERK1 and ERK2 cascade	IDA IDA: 通过直接分析推断	16858399	MGI
acts upstream of angiogenesis	IGI IGI: 通过遗传相互作用推断	16648142	MGI
acts upstream of canonical Wnt signaling pathway	IDA IDA: 通过直接分析推断	16858399	MGI
acts upstream of cell population proliferation	IDA IDA: 通过直接分析推断	16141225	MGI
acts upstream of cell population proliferation	IGI IGI: 通过遗传相互作用推断	10027293	MGI
acts upstream of cerebellar granule cell precursor proliferation	IDA IDA: 通过直接分析推断	10027293	MGI
acts upstream of or within corticotropin hormone secreting cell differentiation	IDA IDA: 通过直接分析推断	9463347	MGI
acts upstream of endothelial cell migration	IDA IDA: 通过直接分析推断	16291864	MGI
acts upstream of endothelial cell proliferation	IDA IDA: 通过直接分析推断	16291864	MGI
acts upstream of epithelial cell proliferation	IDA IDA: 通过直接分析推断	17187775	MGI
acts upstream of epithelial cell proliferation	IGI IGI: 通过遗传相互作用推断	15509736	MGI
acts upstream of or within glial cell differentiation	IMP IMP: 通过突变表型推断	12878680	MGI
acts upstream of inner ear auditory receptor cell differentiation	IDA IDA: 通过直接分析推断	12417662	MGI
acts upstream of or within lung development	IDA IDA: 通过直接分析推断	15576401	MGI
acts upstream of or within lung development	IGI IGI: 通过遗传相互作用推断	17187775	MGI
acts upstream of lymphatic endothelial cell migration	IDA IDA: 通过直接分析推断	16291864	MGI
acts upstream of or within mammary gland epithelial cell differentiation	IDA IDA: 通过直接分析推断	1376141	MGI
acts upstream of or within negative regulation of cell population proliferation	IGI IGI: 通过遗传相互作用推断	10027293	MGI
acts upstream of or within negative regulation of stem cell proliferation	IGI IGI: 通过遗传相互作用推断	20570969	MGI
acts upstream of neuroblast proliferation	IGI IGI: 通过遗传相互作用推断	15051883	MGI
acts upstream of neuroepithelial cell differentiation	IDA IDA: 通过直接分析推断	12417662	MGI
acts upstream of or within organ induction	IDA IDA: 通过直接分析推断	15576401	MGI
acts upstream of osteoblast differentiation	IGI IGI: 通过遗传相互作用推断	20570969	MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: 通过直接分析推断	16858399	MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade	IDA IDA: 通过直接分析推断	16858399	MGI
involved in positive regulation of ERK1 and ERK2 cascade	IDA IDA: 通过直接分析推断	29501879	MGI
acts upstream of or within positive regulation of MAPK cascade	IDA IDA: 通过直接分析推断	16339969	MGI
acts upstream of or within positive regulation of angiogenesis	IDA IDA: 通过直接分析推断	14702107	MGI
acts upstream of or within positive regulation of angiogenesis	IGI IGI: 通过遗传相互作用推断	12759260	MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway	IDA IDA: 通过直接分析推断	16858399	MGI
acts upstream of or within positive regulation of cell population proliferation	IDA IDA: 通过直接分析推断	9463347	MGI
acts upstream of or within positive regulation of cerebellar granule cell precursor proliferation	IDA IDA: 通过直接分析推断	10027293	MGI
acts upstream of or within positive regulation of endothelial cell migration	IDA IDA: 通过直接分析推断	16291864	MGI
acts upstream of or within positive regulation of endothelial cell proliferation	IDA IDA: 通过直接分析推断	16291864	MGI
acts upstream of or within positive regulation of epithelial cell proliferation	IDA IDA: 通过直接分析推断	17187775	MGI
acts upstream of or within positive regulation of epithelial cell proliferation	IGI IGI: 通过遗传相互作用推断	15509736	MGI
acts upstream of or within positive regulation of gene expression	IDA IDA: 通过直接分析推断	9244299	MGI
acts upstream of or within positive regulation of inner ear auditory receptor cell differentiation	IDA IDA: 通过直接分析推断	12417662	MGI
acts upstream of or within positive regulation of neuroblast proliferation	IGI IGI: 通过遗传相互作用推断	15051883	MGI
acts upstream of or within positive regulation of neuroepithelial cell differentiation	IDA IDA: 通过直接分析推断	12417662	MGI
acts upstream of or within positive regulation of osteoblast differentiation	IGI IGI: 通过遗传相互作用推断	20570969	MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: 通过直接分析推断	16858399	MGI
acts upstream of or within positive regulation of protein phosphorylation	IDA IDA: 通过直接分析推断	15608665	MGI
involved in positive regulation of protein phosphorylation	IDA IDA: 通过直接分析推断	29501879	MGI
acts upstream of or within positive regulation of stem cell differentiation	IDA IDA: 通过直接分析推断	15781473	MGI
acts upstream of or within positive regulation of stem cell proliferation	IDA IDA: 通过直接分析推断	16141225	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	9102311	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: 通过遗传相互作用推断	8898217	MGI
acts upstream of or within regulation of cell cycle	IDA IDA: 通过直接分析推断	9463347	MGI
acts upstream of or within regulation of retinal cell programmed cell death	IDA IDA: 通过直接分析推断	11747369	MGI
acts upstream of or within response to axon injury	IMP IMP: 通过突变表型推断	16009496	MGI
involved in stem cell development	IMP IMP: 通过突变表型推断	12843296	MGI
acts upstream of stem cell differentiation	IDA IDA: 通过直接分析推断	15781473	MGI
acts upstream of stem cell proliferation	IDA IDA: 通过直接分析推断	16141225	MGI
acts upstream of stem cell proliferation	IGI IGI: 通过遗传相互作用推断	20570969	MGI
acts upstream of or within substantia nigra development	IMP IMP: 通过突变表型推断	17234579	MGI
acts upstream of or within thyroid-stimulating hormone-secreting cell differentiation	IDA IDA: 通过直接分析推断	9463347	MGI
acts upstream of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	10391928	MGI

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in extracellular space	IDA IDA: 通过直接分析推断	12417662	MGI

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

fibroblast growth factor 2

HBGF-2	basic fibroblast growth factor
fibroblast growth factor 2a	heparin-binding growth factor 2

重组 Fgf2 蛋白

目录号	产品名	蛋白编号	纯度
HY-P7066	FGF-2 Protein, Mouse (145a.a)	P15655 (P10-S154)	≥95%
HY-P70439	FGF-2 Protein, Mouse (154a.a)	P15655 (M1-S154)	≥95%
HY-P73052	FGF-2 Protein, Mouse (His)	NP_032032.1 (A11-S154)	≥95%
HY-P73052AF	Animal-Free FGF-2 Protein, Mouse (His)	P15655 (A11-S154)	≥95%

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-122704A	Surfen dihydrochloride	Inhibitor	≥99.0%	否
HY-D0889	Glycylglycine		99.90%	否
HY-107753	XRP44X	Inhibitor	98.09%	否
HY-107194	NSC12	Inhibitor	99.27%	否
HY-P5133	Synstatin (92-119)	Inhibitor	99.42%	否
HY-102071	KIN59	Inhibitor	≥99.0%	否
HY-RS04896	FGF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-172443	Keratin sulfate		84.2%	否
HY-D0889R	Glycylglycine (Standard)		/	否
HY-116030	JNJ-26076713	Antagonist	/	否
HY-118792	AHR activator 1		/	否
HY-122704	Surfen	Inhibitor	/	否
HY-123541	Tec-IN-6	Inhibitor	/	否
HY-124827	Tec-IN-1	Inhibitor	/	否
HY-161840	Antitumor agent-176	Inhibitor	/	否
HY-161841	Antitumor agent-177	Inhibitor	/	否
HY-P10301	CXCL9(74-103)		/	否
HY-P10870	Pep1-DNP conjugate 9		/	否
HY-RS04890	FGF13 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-118184	AF3485	Inhibitor	/	否
HY-123453	SM27	Inhibitor	/	否
HY-138257A	(R)-Indeloxazine benzenesulfonate	Inhibitor	/	否
HY-165603	Si5-N14	Inhibitor	/	否
HY-RS16510	Fgf2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS22942	Fgf2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-W040074	Glycylglycine hydrochloride hydrate		/	否

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P990597	HuGAL-F2	Inhibitor	98.30%	否
HY-P991584	HuGAL-FR21	Inhibitor	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Fgf2	NCBI	NCBI:2247
Macaca fascicularis	Fgf2	NCBI	NCBI:102133679
Susscrofa domestica	Fgf2	NCBI
Rattus norvegicus	Fgf2	NCBI	NCBI:54250

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Fgf2 - fibroblast growth factor 2 Gene

关于 Fgf2

功能概要

Fgf2 基因产物(1)

重组 Fgf2 蛋白

直系同源

热门区域

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Fgf2 - fibroblast growth factor 2 Gene

关于 Fgf2

功能概要

Fgf2 基因产物(1)

重组 Fgf2 蛋白

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z