2. Gene
  3. Gc - GC, vitamin D binding protein Gene

Gc - GC, vitamin D binding protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: DBP; VDB; Vdbp; DBP02

基因 ID: 24384 | 基因类型: protein coding

关于 Gc

功能概要

Enables vitamin D binding activity. Involved in several processes, including female pregnancy; lactation; and response to estradiol. Located in several cellular components, including axon; extracellular space; and perinuclear region of cytoplasm. Biomarker of brain ischemia and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); chronic obstructive pulmonary disease; hepatocellular carcinoma; human immunodeficiency virus infectious disease; and rheumatic fever. Orthologous to human GC (GC vitamin D binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Gc 基因产物(1)

mRNA Protein Name
NM_012564.3 NP_036696.2 vitamin D-binding protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
8660573 RGD
enables vitamin D binding IDA
IDA: 通过直接分析推断
49052 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IEP
IEP: 通过表达模式推断
217634 RGD
involved in lactation IEP
IEP: 通过表达模式推断
217634 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
6321624 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
12144717 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
217634 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
19034485 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
8660573 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19034485 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vitamin D-binding protein

gc-globulin

group specific component

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0561 Spironolactone 99.63% 是
HY-13693 Mometasone furoate Agonist 99.86% 是
HY-108741 Plecanatide Agonist 99.93% 否
HY-17569 Difluprednate Inhibitor 99.64% 是
HY-108741A Plecanatide acetate Agonist 99.51% 否
Clinical Phase
生物活性分子 (16)
目录号 产品名 作用方式
纯度 Phase
HY-109110 Avasopasem manganese 96.07% Phase 3
HY-14823 Sobetirome Agonist 99.91% Phase 2
HY-P0118B Disitertide diammonium 99.53% Phase 2
HY-14181 Cinaciguat Activator 99.15% Phase 2
HY-10498 Lexibulin 99.10% Phase 2
HY-13336 Imisopasem manganese 98.15% Phase 2
HY-14181A Cinaciguat hydrochloride Activator 98.90% Phase 2
HY-P0118 Disitertide / Phase 2
HY-132829 Rucosopasem manganese / Phase 2
HY-P0118A Disitertide TFA / Phase 2
HY-10498A Lexibulin dihydrochloride / Phase 2
HY-114577 Palifosfamide tromethamine Chemical / Phase 2
HY-145381 11β-HSD1-IN-6 Inhibitor / Phase 2
HY-P3499 Dolcanatide Agonist 99.20% Phase 1
HY-12946 BI 653048 Inhibitor 99.84% Phase 1
HY-12946A BI 653048 phosphate Inhibitor / Phase 1
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P99693 Lenvervimab Inhibitor ≥99% Phase 3
HY-P99013 Codrituzumab Inhibitor 99.07% Phase 2
HY-P99020 Fresolimumab Inhibitor 99.51% Phase 2
Pre-clinical Phase
生物活性分子 (64)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108314A GC7 Sulfate Inhibitor 98.0% 否
HY-D1020 7-Aminoactinomycin D Inhibitor ≥99.0% 否
HY-136684 BrBzGCp2 Inhibitor 99.00% 否
HY-W127512 5β-Cholanic acid 99.87% 否
HY-111798A Heme Oxygenase-1-IN-1 hydrochloride Inhibitor 99.03% 否
HY-111798 Heme Oxygenase-1-IN-1 Inhibitor 99.11% 否
HY-141513 NH-3 Antagonist 99.41% 否
HY-13963 ZCL278 Inhibitor 98.49% 否
HY-111208 CCT129957 Inhibitor 99.71% 否
HY-W040129 Chromomycin A3 99.66% 否
HY-100721 GC376 sodium Inhibitor 98.69% 否
HY-19345A Vacquinol-1 dihydrochloride Activator 99.70% 否
HY-108628 SU16f Inhibitor 99.36% 否
HY-I0450 Anticancer agent 265 99.74% 否
HY-132184 5,6-Epoxyeicosatrienoic acid Inhibitor 99.00% 否
HY-W004290 Methyl heptadecanoate 98.85% 否
HY-W004290S Methyl heptadecanoate-d33 99.04% 否
HY-152038 SPEN-IN-1 98.47% 否
HY-130189 S-Phenylmercapturic acid 99.38% 否
HY-W089645 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide 98.79% 否
HY-114043 NCGC00092410 Inhibitor 99.54% 否
HY-131389 Cholesteryl heptadecanoate 98.0% 否
HY-149453 MCUF-651 Modulator 99.85% 否
HY-151482 SARS-CoV-2 Mpro-IN-2 Inhibitor 98.96% 否
HY-155789 C17 Globotriaosylceramide (d18:1/17:0) ≥99.0% 否
HY-108314 GC-7 Inhibitor / 否
HY-161177 PROTAC KRAS G12D degrader 2 Inhibitor / 否
HY-107547 BPIPP Inhibitor 98.3% 否
HY-160178 Glucocorticoid receptor agonist-3 Ala-Ala-Mal 99.72% 否
HY-101282 Glutaminyl Cyclase Inhibitor 3 Inhibitor / 否
HY-108353S Isoprenaline-d7 acetate / 否
HY-118274 ADDA / 否
HY-130229 (±)5,6-DHET lactone / 否
HY-146398 AMPK activator 6 Activator / 否
HY-14823G Sobetirome (GMP) Agonist / 否
HY-148392 Neu5Gcα(2-6) N-Glycan-Asn / 否
HY-149774 GC-78-HCl / 否
HY-156020 Glucocerebrosidase-IN-2 Inhibitor / 否
HY-157001 7-Deaza-dGTP tetralithium / 否
HY-160180 Glucocorticoid receptor agonist-4 Ala-Ala-Mal / 否
HY-162293 CDK8-IN-14 Inhibitor / 否
HY-166965 Neu5Gc(α2,6)N-Acetylgalactosamine / 否
HY-19345 Vacquinol-1 Activator / 否
HY-N15629 Melicopicine / 否
HY-N15820 C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) / 否
HY-N15822 C18:0 GM3(Neu5Gc) Ceramide (d18:1/18:0) / 否
HY-N15823 C18:0 GM2(Neu5Gc) Ceramide (d18:1/18:0) / 否
HY-P10090 Apoptin-derived peptide / 否
HY-P10786 LinTT1 peptide Inhibitor / 否
HY-P1911 CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156) / 否
HY-RS05316 GC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W127357 Tripelargonin / 否
HY-W127496 Methyl 13-methyltetradecanoate / 否
HY-W130478S 1-Phenylhexane-d5 / 否
HY-120410 DL-4662 / 否
HY-132184S 5,6-Epoxyeicosatrienoic acid-d11 / 否
HY-154171 Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one / 否
HY-165420 GC-IN-2 Inhibitor / 否
HY-N10626 Neu5Gcα(2-6) N-Glycan / 否
HY-RS16765 Gc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20039 Il2rg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20738 Gba1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23205 Gc Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-111442 GC 14 Antagonist / 否
抗体抑制剂 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990844 Anti-GC1q R/C1QBP Antibody (60.11) Inhibitor / 否
HY-P991302 KL-A289 Inhibitor / 否
HY-P991482 ADI-42898 Inhibitor / 否
HY-P991571 GC1118 Inhibitor / 否
HY-P991582 BI-1607 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gc NCBI NCBI:2638
Canis familiaris Gc NCBI NCBI:475172
Macaca fascicularis Gc NCBI NCBI:102135316
Mus musculus Gc NCBI NCBI:14473
Susscrofa domestica Gc NCBI
Leporidae Gc NCBI
Macaca mulatta Gc NCBI NCBI:705708
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