1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Glucocorticoid Receptor
    HCV Protease
  3. BI 653048

BI 653048 

目录号: HY-12946
产品使用指南

BI 653048 是一种选择性的口服活性非甾体类糖皮质激素 (GC) 激动剂,具有抗炎作用。 BI 653048 是从专利 WO2005028501A1 中获得,化合物 103,也是一种 HCV NS3 protease 蛋白酶抑制剂,可以减少感染丙型肝炎病毒的病毒载量。

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BI 653048 Chemical Structure

BI 653048 Chemical Structure

CAS No. : 1198784-72-3

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Description

BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects[1]. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[2].

IC50 & Target

IC50: Glucocorticoid (GC)[1]

Molecular Weight

515.52

Formula

C₂₃H₂₅F₄N₃O₄S

CAS No.

1198784-72-3

SMILES

O=C(N)C1=CC(F)=CC=C1C(C)(C)C[C@@](O)(CC(N2)=CC3=C2C=NC(S(=O)(CC)=O)=C3)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BI 653048BI653048BI-653048Glucocorticoid ReceptorHCV ProteaseHCVNS3proteaseInhibitorinhibitorinhibit

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产品名称:
BI 653048
目录号:
HY-12946
需求量: