2. Gene
  3. Ahr - aryl hydrocarbon receptor Gene

Ahr - aryl hydrocarbon receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25690 | 基因类型: protein coding

关于 Ahr

功能概要

Enables nuclear receptor activity and toxic substance binding activity. Involved in several processes, including cellular response to organic cyclic compound; negative regulation of Alkaline Phosphatase activity; and regulation of cellular macromolecule biosynthetic process. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (Aryl Hydrocarbon Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ahr 基因产物(3)

mRNA Protein Name
NM_001308254.1 NP_001295183.1 aryl hydrocarbon receptor isoform 2
NM_001308255.1 NP_001295184.1 aryl hydrocarbon receptor isoform 3
NM_013149.3 NP_037281.3 aryl hydrocarbon receptor isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arachidonate omega-hydroxylase activity IMP
IMP: 通过突变表型推断
19889059 RGD
enables nuclear receptor activity IDA
IDA: 通过直接分析推断
7812217 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11259609 RGD
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
9056263 RGD
enables sequence-specific double-stranded DNA binding IMP
IMP: 通过突变表型推断
15492120 RGD
enables toxic substance binding IDA
IDA: 通过直接分析推断
18938125 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aflatoxin metabolic process IEP
IEP: 通过表达模式推断
28959666 RGD
involved in cellular response to 2,3,7,8-tetrachlorodibenzodioxine IDA
IDA: 通过直接分析推断
9658193 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
9804617 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
17690134 RGD
involved in cellular response to toxic substance IMP
IMP: 通过突变表型推断
31746392 RGD
involved in circadian rhythm IEP
IEP: 通过表达模式推断
9813174 RGD
involved in conditioned taste aversion IMP
IMP: 通过突变表型推断
30769105 RGD
involved in contact inhibition IMP
IMP: 通过突变表型推断
17952121 RGD
involved in estrogen receptor signaling pathway IDA
IDA: 通过直接分析推断
26372666 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
21666223 RGD
involved in mammary duct terminal end bud growth IDA
IDA: 通过直接分析推断
26372666 RGD
involved in negative regulation of DNA biosynthetic process IDA
IDA: 通过直接分析推断
12193573 RGD
involved in negative regulation of DNA biosynthetic process IMP
IMP: 通过突变表型推断
17952121 RGD
involved in negative regulation of alkaline phosphatase activity IDA
IDA: 通过直接分析推断
12193573 RGD
involved in negative regulation of calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
12193573 RGD
involved in negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
17952121 RGD
involved in negative regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
12193573 RGD
involved in negative regulation of osteoblast proliferation IDA
IDA: 通过直接分析推断
12193573 RGD
involved in nitric oxide metabolic process IEP
IEP: 通过表达模式推断
31489946 RGD
involved in omega-hydroxylase P450 pathway IMP
IMP: 通过突变表型推断
19889059 RGD
involved in ovarian follicle development IMP
IMP: 通过突变表型推断
20466593 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
32913241 RGD
involved in positive regulation of mating-type specific transcription, DNA-templated IDA
IDA: 通过直接分析推断
9056263 RGD
involved in protein localization to nucleus IMP
IMP: 通过突变表型推断
32913241 RGD
involved in reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
35788946 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
7812217 RGD
involved in regulation of cytokine production IMP
IMP: 通过突变表型推断
33766215 RGD
involved in regulation of eating behavior IDA
IDA: 通过直接分析推断
27594096 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
23999541 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
20176079 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18059014 RGD
involved in response to organic cyclic compound IMP
IMP: 通过突变表型推断
20403408 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
9653054 RGD
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
9658193 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
10053172 RGD
involved in tissue remodeling IEP
IEP: 通过表达模式推断
23887904 RGD
involved in transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7812217 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18515748 RGD
located in nucleus IDA
IDA: 通过直接分析推断
7812217 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aryl hydrocarbon receptor

ah receptor

相关产品

Approval
生物活性分子 (11)
目录号 产品名 作用方式
纯度 是否罕见病
HY-109044 Tapinarof Agonist 99.95% 否
HY-N0178 Diosmin Agonist 99.51% 是
HY-A0083 Methacholine chloride Agonist ≥98.0% 是
HY-B0311 Carbidopa Modulator ≥98.0% 是
HY-B0678 Metaxalone 99.77% 否
HY-17357 Nepafenac Inhibitor 99.56% 否
HY-W017113 2-Mercaptobenzothiazole Activator 99.85% 是
HY-B0311A Carbidopa monohydrate Modulator ≥98.0% 是
HY-17479 Amfenac / 否
HY-A0083B Methacholine bromide Agonist / 否
HY-B0678R Metaxalone (Standard) / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-B2132 Tryptamine 99.77% Phase 3
HY-15001 Stemregenin 1 Antagonist 99.95% Phase 2
HY-N0170 Indole-3-carbinol 98.87% Phase 2
HY-16031 AFP464 free base Inhibitor / Phase 2
HY-111449 BAY-218 Antagonist 99.78% Phase 1
Pre-clinical Phase
生物活性分子 (136)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12028 PD98059 99.94% 否
HY-12684 CH-223191 Antagonist 99.96% 否
HY-15484 Pifithrin-α hydrobromide 98.58% 否
HY-12451 FICZ Agonist 99.42% 否
HY-W028393 Indole-3-pyruvic acid Agonist 99.79% 否
HY-135829 BAY 2416964 Antagonist 99.59% 否
HY-19317 ITE Agonist 99.27% 否
HY-W007355 Skatole 99.98% 否
HY-W015273A trans-3-Indoleacrylic acid Inhibitor 99.39% 否
HY-102023 GNF351 Antagonist 99.87% 否
HY-114740 β-Naphthoflavone 99.94% 否
HY-103220 6,2',4'-Trimethoxyflavone Antagonist 98.02% 否
HY-N1939 Icariside I 99.30% 否
HY-122208 SGA360 Inhibitor 99.93% 否
HY-W011338 Benzyl butyl phthalate Activator ≥97.0% 否
HY-134217 KYN-101 Inhibitor 98.03% 否
HY-135750 VAF347 Agonist 99.75% 否
HY-W014502 D-Kynurenine Agonist 99.67% 否
HY-103221 MeBIO ≥98.0% 否
HY-141609 IK-175 Inhibitor 99.78% 否
HY-119019 ASB14780 Inhibitor 99.83% 否
HY-18619 YL-109 Modulator 99.26% 否
HY-112628 CAY10464 Antagonist 99.77% 否
HY-144339 AhR agonist 2 99.89% 否
HY-B0845 Prochloraz 99.85% 否
HY-W014075 1-Hydroxypyrene 99.84% 否
HY-112629 PDM2 Antagonist 98.96% 否
HY-12545 Brevetoxin-3 Activator 95.0% 否
HY-112627 CAY 10465 Agonist 98.30% 否
HY-15001G Stemregenin 1 (GMP) Antagonist / 否
HY-N0914 Ajugol 99.13% 否
HY-117532 PenCB Inducer 99.94% 否
HY-118438 10-Cl-BBQ Agonist 99.48% 否
HY-130256 β-NF-JQ1 Inhibitor 98.05% 否
HY-111450 CB7993113 Antagonist ≥98.0% 否
HY-124421 5F-203 Inducer 99.04% 否
HY-135831 AHR antagonist 2 Antagonist 99.30% 否
HY-D0932 Sudan IV ≥98.0% 否
HY-N4095 Brevifolincarboxylic acid Inhibitor 99.90% 否
HY-117102 ANI-7 Activator 99.01% 否
HY-77278 25-Hydroxytachysterol3 Agonist 98.89% 否
HY-105791 Sulazepam 99.56% 否
HY-114682 Lenperone Antagonist 98.11% 否
HY-N0586 Norisoboldine Agonist / 否
HY-W011338S Benzyl butyl phthalate-d4 98.38% 否
HY-W014701 1,4-Dihydroxy-2-naphthoic acid 99.60% 否
HY-111441 1,4-Chrysenequinone Activator 98.42% 否
HY-125019 iJak-381 Inhibitor 99.86% 否
HY-17357S Nepafenac-d5 Inhibitor 98.84% 否
HY-N0586A Norisoboldine hydrochloride Agonist 99.72% 否
HY-N6264 26-Deoxyactein Inhibitor 99.76% 否
HY-W718300 Indole-3-pyruvic acid-d5 96.02% 否
HY-W764758 3-OH-Kynurenamine dihydroiodide Activator 99.56% 否
HY-100242 Mivotilate Activator 99.58% 否
HY-103223 Phortress Inducer 99.25% 否
HY-N10123 Indolokine A5 Agonist ≥98.0% 否
HY-RS00483 AHR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W014075S 1-Hydroxypyrene-d9 99.95% 否
HY-W251708 AHR 10240 / 否
HY-136220 AHR antagonist 5 Antagonist 98.05% 否
HY-103222 DiMNF Modulator 98.46% 否
HY-104026CS L-Kynurenine-13C10 sulfate hemihydrate Agonist 99.90% 否
HY-118474 GW 610 Activator 99.78% 否
HY-118780 CHD-5 Antagonist ≥98.0% 否
HY-16031B AFP464 dihydrochloride Inhibitor 99.67% 否
HY-W046846 Corannulene Agonist ≥97.0% 否
HY-W338764 AHR agonist 3 99.79% 否
HY-154825 20-Hydroxyvitamin D3 ≥98.0% 否
HY-B0973 Dibenzothiophene Inhibitor 99.88% 否
HY-N10295 Flavipin Agonist / 否
HY-131340 LASSBio-1632 Inhibitor / 否
HY-136220A AHR antagonist 5 hemimaleate Antagonist / 否
HY-101802 Fluzinamide / 否
HY-104026B L-Kynurenine sulfate Agonist / 否
HY-106487 Pridefine Inhibitor / 否
HY-111157 Dezinamide / 否
HY-114682A Lenperone hydrochloride Antagonist / 否
HY-116148 AHR-11797 / 否
HY-116638 AHR-5333 Inhibitor / 否
HY-116638A AHR-5333 (mandelate) Inhibitor / 否
HY-117774 AHR-2244 hydrochloride / 否
HY-118792 AHR activator 1 / 否
HY-119018 AHR-6293 Inhibitor / 否
HY-119960 AHR-10037 Inhibitor / 否
HY-120377 CYP1A1 inhibitor 8a Inhibitor / 否
HY-120677 AHR-15010 Inhibitor / 否
HY-123432 AHR-13268D Inhibitor / 否
HY-123461 Sul-121 hydrochloride Inhibitor / 否
HY-124021 Benzyl 2-naphthyl ether / 否
HY-125926S 2-Ketodoxapram-d5 / 否
HY-125926S1 2-Ketodoxapram-d4 / 否
HY-129305 Tampramine fumarate Inhibitor / 否
HY-130269 β-Naphthoflavone-CH2-OH / 否
HY-130270 AhR Ligand-Linker Conjugates 1 / 否
HY-130842 β-Naphthoflavone-CH2-Br / 否
HY-135671 AhR modulator-1 / 否
HY-135830 AHR antagonist 4 Antagonist / 否
HY-136891 AHR-16303B / 否
HY-139117 6,2′,4′-Trimethoxyflavone Antagonist / 否
HY-155505 AHR agonist 4 Agonist / 否
HY-156908 3-OH-Kynurenamine Activator / 否
HY-158167 AhR agonist 5 Agonist / 否
HY-158168 AhR agonist 6 Agonist / 否
HY-158169 AhR agonist 7 Agonist / 否
HY-161649 hCYP1B1-IN-2 Inhibitor / 否
HY-168033 AhR agonist 8 Agonist / 否
HY-169753 AHR-IN-1 Inhibitor / 否
HY-17479B Amfenac sodium / 否
HY-176771 Tapinarof prodrug-1 / 否
HY-19826 Isofistularin-3 / 否
HY-A0083C Methacholine iodide Agonist / 否
HY-B0311AS Carbidopa-d3 monohydrate Modulator ≥98.0% 否
HY-B0311D Carbidopa hydrochloride Modulator / 否
HY-B0311S1 Carbidopa-d3-1 Modulator / 否
HY-B0678S Metaxalone-d3 ≥98.0% 否
HY-B0678S1 Metaxalone-d6 / 否
HY-B0973S Dibenzothiophene-d8 Inhibitor / 否
HY-N12537A (2R,3S)-PD-1/PD-L1-IN-38 / 否
HY-W014502R D-Kynurenine (Standard) Agonist / 否
HY-W517076 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin Agonist / 否
HY-W716464 Prochloraz-d7 / 否
HY-101745 Rocastine Antagonist / 否
HY-104026BS L-Kynurenine-13C10 sulfate Agonist / 否
HY-107063 AHR-1911 Activator / 否
HY-109044S Tapinarof-d5 Agonist / 否
HY-118910 AHR-14310C Antagonist / 否
HY-119991 AHR-9294 Inhibitor / 否
HY-128229 AHR antagonist 6 Antagonist / 否
HY-130456 AHR 10718 Inhibitor / 否
HY-163665 AHR antagonist 8 / 否
HY-170514 1,2,3,7,8,9-Hexachlorodibenzofuran Ligand / 否
HY-D0932S Sudan IV-d6 / 否
HY-RS16533 Ahr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22964 Ahr Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-U00010 Dazopride / 否
HY-N2462 Hexachlorobenzene Activator / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ahr NCBI NCBI:196
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