2. Gene
  3. Irf3 - interferon regulatory factor 3 Gene

Irf3 - interferon regulatory factor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 292892 | 基因类型: protein coding

关于 Irf3

功能概要

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and protein homodimerization activity. Involved in cellular response to exogenous dsRNA; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of cytokine production. Predicted to be located in cytosol and mitochondrion. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human IRF3 (interferon regulatory factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Irf3 基因产物(1)

mRNA Protein Name
NM_001006969.1 NP_001006970.1 interferon regulatory factor 3
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to exogenous dsRNA IEP
IEP: 通过表达模式推断
18223009 RGD
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
20670634 RGD
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
20670634 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon regulatory factor 3

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-176426 Subquinocin / Phase 4
HY-10249 GSK-690693 99.03% Phase 1
Pre-clinical Phase
生物活性分子 (45)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12326A c-di-AMP disodium Agonist 99.14% 否
HY-P1934 Cyclo(Phe-Pro) Inhibitor 98.77% 否
HY-160225 ISD sodium Activator 98.02% 否
HY-101950 KIN1148 Inhibitor 98.0% 否
HY-P1680 Astin C Inhibitor 99.47% 否
HY-113469 Cyclic GMP 99.77% 否
HY-113469A Cyclic GMP sodium 99.89% 否
HY-139056 SU0268 Inhibitor 99.96% 否
HY-W140974 SN-001 Inhibitor 98.94% 否
HY-152956 STING agonist-23 Agonist 99.33% 否
HY-12326B c-di-AMP diammonium Agonist 99.36% 否
HY-156449 STING-IN-7 Inhibitor 98.75% 否
HY-D0162 Malachite green hemioxalate 98.0% 否
HY-124652 TBK1/IKKε-IN-4 Inhibitor 99.42% 否
HY-112951 ChX710 99.91% 否
HY-123805 KIN1400 98.1% 否
HY-126113 KIN101 Inhibitor 99.44% 否
HY-12326 c-di-AMP Agonist 99.29% 否
HY-113469B Cyclic GMP (TBAOH) 99.07% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-176192 SMU-14a Inhibitor / 否
HY-148606 STING modulator-3 Inhibitor / 否
HY-148645 STING modulator-4 Modulator / 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-160222 HSV-60mer sodium Activator / 否
HY-173399 hSTING activator-1 / 否
HY-173462 TBK1-IN-2 Inhibitor / 否
HY-174308 ZSA-215 Agonist / 否
HY-175714 STING agonist-46 Agonist / 否
HY-177338 STING agonist-45 Agonist / 否
HY-178047 UM-242 Inhibitor / 否
HY-178049 UM-259 Inhibitor / 否
HY-178690 MyD88-IN-4 Inhibitor / 否
HY-178915 ITA-5 Inhibitor / 否
HY-178916 ITA-9 Inhibitor / 否
HY-178951 STING-IN-17 Inhibitor / 否
HY-RS06907 IRF3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W654000 Cyclic GMP-13C,15N2 / 否
HY-W767865 Cyclic GMP sodium-13C5 / 否
HY-149724 Anti-inflammatory agent 65 Inhibitor / 否
HY-N3548 Catalpalactone Inhibitor / 否
HY-RS16587 Irf3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23022 Irf3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Irf3 NCBI NCBI:3661
Mus musculus Irf3 NCBI NCBI:54131
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