1. Gene
  2. Skp2 - S-phase kinase associated protein 2 Gene

Skp2 - S-phase kinase associated protein 2 Gene

种属: Rattus norvegicus

同用名: RGD1562456

基因 ID: 294790 | 基因类型: protein coding

关于 Skp2

功能概要

Predicted to enable identical protein binding activity. Involved in cellular response to cell-matrix adhesion and positive regulation of smooth muscle cell proliferation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Predicted to be active in cytosol and nucleus. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Skp2 基因产物(1)

mRNA Protein Name
NM_001106416.2 NP_001099886.1 S-phase kinase-associated protein 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19533683 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cell-matrix adhesion IEP
IEP: 通过表达模式推断
11425869 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
19878790 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

S-phase kinase-associated protein 2

S-phase kinase-associated protein 2 (p45)

S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Skp2 NCBI NCBI:6502