2. Gene
  3. Eef2 - eukaryotic translation elongation factor 2 Gene

Eef2 - eukaryotic translation elongation factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ef-2

基因 ID: 29565 | 基因类型: protein coding

关于 Eef2

功能概要

Enables several functions, including 5S rRNA binding activity; actin filament binding activity; and p53 binding activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; positive regulation of cytoplasmic translation; and response to ischemia. Located in cytosol; membrane raft; and polysomal ribosome. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Eef2 基因产物(1)

mRNA Protein Name
NM_017245.2 NP_058941.1 elongation factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5S rRNA binding IDA
IDA: 通过直接分析推断
3801485 RGD
enables RNA binding IDA
IDA: 通过直接分析推断
11681712 RGD
enables actin filament binding IDA
IDA: 通过直接分析推断
7988728 RGD
enables p53 binding IPI
IPI: 通过物理相互作用推断
12891704 RGD
enables ribosome binding IDA
IDA: 通过直接分析推断
2390990 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to brain-derived neurotrophic factor stimulus IEP
IEP: 通过表达模式推断
19625250 RGD
involved in glial cell proliferation IEP
IEP: 通过表达模式推断
7696190 RGD
involved in positive regulation of cytoplasmic translation IMP
IMP: 通过突变表型推断
19625250 RGD
involved in positive regulation of translation IDA
IDA: 通过直接分析推断
2390990 RGD
involved in response to endoplasmic reticulum stress IEP
IEP: 通过表达模式推断
18188169 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16339744 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
12899944 RGD
involved in response to folic acid IEP
IEP: 通过表达模式推断
12899944 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
15211596 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
15211596 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16817885 RGD
involved in skeletal muscle cell differentiation IEP
IEP: 通过表达模式推断
16682826 RGD
involved in skeletal muscle contraction IEP
IEP: 通过表达模式推断
19188248 RGD
involved in translation at postsynapse IDA
IDA: 通过直接分析推断
20427644 RGD
involved in translation at postsynapse IEP
IEP: 通过表达模式推断
20427644 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12891704 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20427644 RGD
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
3801485 RGD
located in ribosome IDA
IDA: 通过直接分析推断
12891704 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

elongation factor 2

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-117684 Cabamiquine Inhibitor 99.93% Phase 2
HY-117684A Cabamiquine succinate Inhibitor 99.80% Phase 2
Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12320 Cycloheximide Inhibitor 99.82% 否
HY-110096 A-484954 Inhibitor 99.34% 否
HY-100576 NH125 Inhibitor 99.63% 否
HY-126396 Sordarin sodium Inhibitor 99.0% 否
HY-146324 PROTAC eEF2K degrader-1 Activator 98.64% 否
HY-120904 AMPK-IN-1 Activator 95.19% 否
HY-112393 TX-1918 Inhibitor / 否
HY-121828 TX-1123 Inhibitor / 否
HY-123024 Cefatrizine / 否
HY-176149 Fluoxetine-Conjugated Platinum(IV) prodrug-1 / 否
HY-177720 eEF2K degrader-2 / 否
HY-RS04180 EEF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04181 EEF2K Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20013 Eef2k Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20725 Eef2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26516 Eef2k Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27237 Eef2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eef2 NCBI NCBI:1938
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