2. Gene
  3. Pck1 - phosphoenolpyruvate carboxykinase 1 Gene

Pck1 - phosphoenolpyruvate carboxykinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: GTP; PCK; Pepck; PEPCK-C; RATPEPCK

基因 ID: 362282 | 基因类型: protein coding

关于 Pck1

功能概要

Enables several functions, including guanyl ribonucleotide binding activity; manganese ion binding activity; and nucleoside diphosphate kinase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to hexose stimulus; and cellular response to organonitrogen compound. Located in cytoplasm. Used to study type 2 diabetes mellitus. Biomarker of non-alcoholic steatohepatitis. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pck1 基因产物(1)

mRNA Protein Name
NM_198780.3 NP_942075.1 phosphoenolpyruvate carboxykinase, cytosolic [GTP]
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP binding IDA
IDA: 通过直接分析推断
16125296 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
17685635 RGD
enables carboxylic acid binding IDA
IDA: 通过直接分析推断
17685635 RGD
enables manganese ion binding IDA
IDA: 通过直接分析推断
17685635 RGD
enables nucleoside diphosphate kinase activity EXP
EXP: 通过实验结果推断
1383219 RGD
enables phosphoenolpyruvate carboxykinase (GTP) activity IDA
IDA: 通过直接分析推断
4186849 RGD
enables phosphoenolpyruvate carboxykinase activity IDA
IDA: 通过直接分析推断
4303362 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular hyperosmotic response IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular hyperosmotic salinity response IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular hypotonic response IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular hypotonic salinity response IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular response to fructose stimulus IEP
IEP: 通过表达模式推断
21212096 RGD
involved in cellular response to glucagon stimulus IEP
IEP: 通过表达模式推断
18335579 RGD
involved in cellular response to glucose stimulus IDA
IDA: 通过直接分析推断
30193097 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
24177414 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
18335579 RGD
involved in cellular response to phorbol 13-acetate 12-myristate IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular response to raffinose IEP
IEP: 通过表达模式推断
9530152 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
21519922 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
18335579 RGD
involved in gluconeogenesis IDA
IDA: 通过直接分析推断
4186849 RGD
involved in glucose homeostasis IDA
IDA: 通过直接分析推断
4186849 RGD
involved in glucose metabolic process IMP
IMP: 通过突变表型推断
18055057 RGD
involved in glycerol biosynthetic process from pyruvate IDA
IDA: 通过直接分析推断
4186849 RGD
involved in oxaloacetate metabolic process IDA
IDA: 通过直接分析推断
4303362 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
16458327 RGD
involved in response to interleukin-6 IEP
IEP: 通过表达模式推断
17805558 RGD
involved in response to lipid IEP
IEP: 通过表达模式推断
21486814 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19268478 RGD
involved in response to methionine IEP
IEP: 通过表达模式推断
23052097 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
23307605 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
4186849 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphoenolpyruvate carboxykinase, cytosolic [GTP]

phosphoenolpyruvate carboxykinase (GTP)

phosphoenolpyruvate carboxykinase 1 (soluble)

phosphoenolpyruvate carboxykinase 1, cytosolic

phosphoenolpyruvate carboxykinase, cytosolic (GTP)

phosphoenolpyruvate carboxylase

serine-protein kinase PCK1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10152 PCK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17590 Pck1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24050 Pck1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pck1 NCBI NCBI:5105
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