2. Gene
  3. Hdac10 - histone deacetylase 10 Gene

Hdac10 - histone deacetylase 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：组蛋白脱乙酰酶 10

种属: Rattus norvegicus

基因 ID: 362981 | 基因类型: protein coding

关于 Hdac10

Primary_assembly 7: 120,199,129-120,204,228 reverse strand.mRatBN7.2:CM026980.1

This gene has 3 transcripts (splice variants), 181 orthologues, 12 paralogues and is associated with 4 phenotypes. Biased expression in Muscle (RPKM 36.9), Thymus (RPKM 35.1) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动组蛋白脱乙酰酶活性；组蛋白脱乙酰酶结合活性；和锌离子结合活性。参与少突胶质细胞发育。预测位于细胞质和核质中。预计是组蛋白脱乙酰酶复合物的一部分。与人类 HDAC10（组蛋白脱乙酰酶 10）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable histone deacetylase activity; histone deacetylase binding activity; and zinc ion binding activity. Involved in oligodendrocyte development. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC10 (histone deacetylase 10). [provided by Alliance of Genome Resources, Apr 2022]

Hdac10 基因产物(1)

mRNA Protein Name
NM_001035000.1 NP_001030172.1 polyamine deacetylase HDAC10
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in oligodendrocyte development IEP
IEP: 通过表达模式推断
18627006 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Hdac10 蛋白结构

Arginase_HDAC

Arginase_HDAC: cl17011 (17 - 353)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
蛋白主名 其他名称

polyamine deacetylase HDAC10

HD10

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-109015 Tucidinostat Inhibitor 98.60% 否
HY-14842 Givinostat Inhibitor 98.67% 是
HY-13322 Pracinostat Inhibitor 99.80% 是
HY-B0494 Bufexamac Inhibitor 98.0% 否
Clinical Phase
生物活性分子 (10)
目录号 产品名 作用方式
纯度 Phase
HY-10990 Abexinostat Inhibitor 99.00% Phase 3
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Phase 3
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Phase 3
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Phase 2
HY-101780 Tinostamustine Inhibitor 99.64% Phase 2
HY-16012A Domatinostat Inhibitor 99.34% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2
HY-10223 CUDC-101 Inhibitor 99.05% Phase 1
Pre-clinical Phase
生物活性分子 (36)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13428 Tubacin Inhibitor 99.54% 否
HY-15224 PCI-34051 Inhibitor 99.84% 否
HY-18613 CAY10603 Inhibitor 99.76% 否
HY-16699 Nexturastat A Inhibitor 98.28% 否
HY-111818 TH34 Inhibitor 99.52% 否
HY-144779 HDAC10-IN-1 Inhibitor 99.87% 否
HY-115475 SW-100 Inhibitor 99.93% 否
HY-19747 HPOB Inhibitor 99.80% 否
HY-150109 Purinostat mesylate Inhibitor 99.45% 否
HY-110280 MC1742 Inhibitor 98.95% 否
HY-174444 PROTAC HDAC degrader-2 Degrader / 否
HY-109015S Tucidinostat-d4 Inhibitor 98.63% 否
HY-19754A CRA-026440 hydrochloride Inhibitor 98.12% 否
HY-152174 HDAC-IN-52 Inhibitor 99.46% 否
HY-161778 ZG-126 Inhibitor / 否
HY-163430 HDAC-IN-71 Inhibitor / 否
HY-147731 HDAC6-IN-9 Inhibitor / 否
HY-152173 HDAC-IN-51 Inhibitor / 否
HY-163834 HDAC6-IN-47 Inhibitor / 否
HY-175030 TNI-97 Inhibitor / 否
HY-174401 PROTAC HDAC6 degrader 5 Inhibitor / 否
HY-162658 Leuxinostat Inhibitor / 否
HY-157740 XSJ-10 Inhibitor / 否
HY-152226 MC2590 Inhibitor 98.71% 否
HY-162630 HDAC6-IN-44 Inhibitor / 否
HY-150595 HDAC6-IN-10 Inhibitor / 否
HY-152225 MC2625 Inhibitor / 否
HY-147966 HDAC-IN-43 Inhibitor / 否
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / 否
HY-144782 HDAC10-IN-2 Inhibitor / 否
HY-163803 CM-444 Inhibitor / 否
HY-124946 C1A Inhibitor / 否
HY-149283 JAK/HDAC-IN-2 Inhibitor / 否
HY-15144B (S)-Trichostatin A Inhibitor / 否
HY-146684 HDAC-IN-36 Inhibitor / 否
HY-19754 CRA-026440 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hdac10 NCBI NCBI:83933
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