2. Gene
  3. H2ax - H2A.X variant histone Gene

H2ax - H2A.X variant histone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: H2afx; RGD1566119

基因 ID: 500987 | 基因类型: protein coding

关于 H2ax

功能概要

Predicted to enable damaged DNA binding activity; enzyme binding activity; and histone binding activity. Involved in several processes, including cellular response to gamma radiation; cellular senescence; and cerebral cortex development. Located in nucleus. Used to study hypertension; status epilepticus; and transient cerebral ischemia. Biomarker of liver benign neoplasm. Orthologous to human H2AX (H2A.X variant histone). [provided by Alliance of Genome Resources, Apr 2022]

H2ax 基因产物(1)

mRNA Protein Name
NM_001109291.2 NP_001102761.1 H2A.X variant histone
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to gamma radiation IDA
IDA: 通过直接分析推断
17552875 RGD
involved in cellular senescence IEP
IEP: 通过表达模式推断
19946210 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
3622934 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
3932111 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

H2A.X variant histone

H2A histone family, member X

相关产品

Clinical Phase
生物活性分子 (8)
目录号 产品名 作用方式
纯度 Phase
HY-12037A Rigosertib 99.01% Phase 3
HY-12037 Rigosertib sodium 99.57% Phase 3
HY-18174 Prexasertib 98.75% Phase 2
HY-18174A Prexasertib dihydrochloride 99.73% Phase 2
HY-18174E Prexasertib dimesylate 98.90% Phase 2
HY-18174B Prexasertib Mesylate Hydrate / Phase 2
HY-177631 Etidaligide Inhibitor / Phase 2
HY-177631A Etidaligide sodium Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (24)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117693 (E/Z)-Mirin Inhibitor 99.22% 否
HY-123834 FEN1-IN-1 99.85% 否
HY-101089 RHPS4 99.88% 否
HY-N0316 Mollugin 99.48% 否
HY-122181B OTS186935 hydrochloride Inhibitor 99.58% 否
HY-122181 OTS186935 Inhibitor 98.55% 否
HY-103241 Ro 90-7501 99.10% 否
HY-122182 OTS193320 98.64% 否
HY-W1126504 ETN029 Ligand 99.91% 否
HY-RS05957 H2AX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-18174C Prexasertib mesylate / 否
HY-122181A OTS186935 trihydrochloride Inhibitor / 否
HY-117688 WJ35435 / 否
HY-121777 SFOM-0046 Inhibitor / 否
HY-122860 SKLB-C05 / 否
HY-145288 Antitumor agent-36 / 否
HY-145289 Antitumor agent-37 / 否
HY-162985 JHD205 Inhibitor / 否
HY-168877 FMP Activator / 否
HY-174989 ATM-IN-2 / 否
HY-175700 YCJ-02 / 否
HY-18174H Prexasertib lactate / 否
HY-RS16644 H2ax Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23078 H2ax Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens H2ax NCBI NCBI:3014
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