1. Apoptosis Autophagy
  2. Apoptosis Autophagy
  3. Glychionide A

Glychionide A  (Synonyms: 去甲汉黄芩素-7-O-葡萄糖醛酸苷)

目录号: HY-N8034 纯度: 99.47%
COA 产品使用指南

Glychionide A 是一种黄酮苷,存在于 Glychirriza glabra 的根中。Glychionide A 促进 PANC-1 胰腺癌细胞的凋亡和自噬。Glychionide A 可用于癌症的研究。

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Glychionide A Chemical Structure

Glychionide A Chemical Structure

CAS No. : 119152-50-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer[1][2].

体外研究
(In Vitro)

Glychionide A (3.12-100 μM) significantly inhibits the proliferation of the PANC-1 pancreatic cancer cells, with an IC50 of 14 μM[1].
Glychionide A (7-28 μM) induces both autophagy and apoptosis in pancreatic cancer cells[1].
Glychionide A (7-28 μM) causes G2/M arrest of PANC-1 pancreatic cancer cells[1].
Glychionide A (7-28 μM) causes generation of ROS in PANC-1 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

446.36

Formula

C21H18O11

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

去甲汉黄芩素-7-O-葡萄糖醛酸苷

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Glychionide A 相关分类

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