1. GPCR/G Protein
  2. Guanylate Cyclase
  3. GSK2181236A

GSK2181236A 是一种对 NO 不敏感的可溶性鸟苷酸环化酶 (sGC) 激活剂。GSK2181236A 能够舒张血管、降低平均动脉压并减轻心脏肥大的发展。GSK2181236A 可用于心血管疾病的研究,如高血压。

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GSK2181236A

GSK2181236A Chemical Structure

CAS No. : 1160426-89-0

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  • 生物活性

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生物活性

GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension[1].

分子量

613.51

Formula

C31H21F6N3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GSK2181236A
目录号:
HY-119081
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