1. Anti-infection Metabolic Enzyme/Protease
  2. HIV HIV Protease
  3. HIV-1 protease-IN-15

HIV-1 protease-IN-15 (Compound 27) 是一种具有口服活性的HIV-1 蛋白酶 (HIV-1 protease) 的选择性抑制剂,pIC50 为 9.347。HIV-1 protease-IN-15 抑制 HIV 蛋白成熟过程,阻断病毒复制。HIV-1 protease-IN-15 有望用于 HIV-1 感染的研究。

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HIV-1 protease-IN-15

HIV-1 protease-IN-15 Chemical Structure

CAS No. : 2986573-09-3

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生物活性

HIV-1 protease-IN-15 (Compound 27) is an orally active and selective inhibitor targeting HIV-1 protease with a pIC50 value of 9.347. HIV-1 protease-IN-15 inhibits HIV protein maturation, blocks viral replication. HIV-1 protease-IN-15 is promising for research of HIV-1 infection[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK-293T CC50
> 100 μM
Compound: 3c
Cytotoxicity against HEK293T cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay
Cytotoxicity against HEK293T cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay
[PMID: 33906049]
分子量

555.65

Formula

C27H36F3N3O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HIV-1 protease-IN-15
目录号:
HY-174998
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