1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. HSP27 inhibitor J2

HSP27 inhibitor J2 (Synonyms: J2)

目录号: HY-124653
产品使用指南

HSP27 inhibitor J2 (J2) 是一种 HSP27 抑制剂,其显著诱导异常 HSP27 二聚体形成并抑制 HSP27 巨聚合物的产生,从而具有抑制 HSP27 的伴侣功能和降低其细胞保护功能的作用。HSP27 inhibitor J2 (J2) 显著增强 17-AAG 的抗增殖活性,并对顺铂诱导的肺癌细胞生长抑制具有敏感性。

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HSP27 inhibitor J2 Chemical Structure

HSP27 inhibitor J2 Chemical Structure

CAS No. : 2133499-85-9

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Description

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2].

IC50 & Target

HSP27[2]

Molecular Weight

264.30

Formula

C₁₃H₁₂O₄S

CAS No.

2133499-85-9

SMILES

O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
HSP27 inhibitor J2
目录号:
HY-124653
需求量:

HSP27 inhibitor J2

Cat. No.: HY-124653