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Kobusine derivative-1 是一种 Kobusine 衍生物,其表现出对癌细胞的抗增殖活性。

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Kobusine derivative-1 Chemical Structure

Kobusine derivative-1 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kobusine derivative-1 is a Kobusine derivative. Kobusine derivative-1 shows antiproliferative activities against cancer cells[1].

体外研究
(In Vitro)

Kobusine derivative-1 (0-20 μM; 72 h) exhibits significant antiproliferative activities against five human cancer cell lines[1].
Kobusine derivative-1 (13.5 μM; 12 or 24 h) treatment likely induces apoptosis within 12 h, decreases numbers of cells in S and G2/M phases, resulting in accumulation of sub-G1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: A549, MDA-MB-231, MCF-7, KB, and KB-VIN cells
Concentration: 0-20 μM
Incubation Time: 72 hours
Result: Inhibited A549, MDA-MB-231, MCF-7, KB, and KB-VIN cells with IC50 values of 4.8, 4.5, 4.7, 4.6, and 4.8 μM, respectively.

Cell Cycle Analysis[1]

Cell Line: MDA-MB-23 cells
Concentration: 13.5 μM
Incubation Time: 12 or 24 hours
Result: Disrupted normal cell cycle progression after 12 h, decreased numbers of cells in S and G2/M phases, resulted in accumulation of sub-G1.
分子量

657.64

Formula

C36H33F6NO4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Kobusine derivative-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Kobusine derivative-1
目录号:
HY-149032
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