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  3. KTX-582 intermediate-3

KTX-582 intermediate-3 是合成 KTX-582 (HY-148274) 的中间体,可用于 ADC 制备。KTX-582 是 IRAK4 降解剂和凋亡 (apoptosis) 诱导剂,对 IRAK4 和 Ikaros 的 DC50 分别为 4 nM 和 5 nM。

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KTX-582 intermediate-3 Chemical Structure

KTX-582 intermediate-3 Chemical Structure

CAS No. : 2573304-30-8

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  • 生物活性

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生物活性

KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

分子量

518.53

Formula

C26H29F3N4O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

KTX-582 intermediate-3 相关分类

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产品名称:
KTX-582 intermediate-3
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HY-49435
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