1. Immunology/Inflammation
  2. NO Synthase
  3. LA-419

LA-419 是一种具有口服活性的一氧化氮 (NO) 供体。LA-419 在感染委内瑞拉钩虫 (S. venezuelensis) 的小鼠中,能显著减少粪便中虫卵的排出量,缩短排虫卵的持续时间,还能减少肺部幼虫的数量以及肠道内寄生雌虫的数量。LA-419 可减轻载脂蛋白 E 缺陷小鼠的动脉粥样硬化形成。LA-419 可用于感染和心血管疾病的研究。

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LA-419

LA-419 Chemical Structure

CAS No. : 263754-93-4

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查看 NO Synthase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease[1].

分子量

249.24

Formula

C8H11NO6S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LA-419
目录号:
HY-19392
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