Maltodextrin, dextrose equivalent 5.0-8.0  (Synonyms: 麦芽糊精,葡萄糖当量5.0-8.0)

Maltodextrin, dextrose equivalent 5.0-8.0 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs^[1].

Maltodextrin, dextrose equivalent 5.0-8.0 是一种具有良好生物相容性和药物包封能力的多糖，其包封 BSA 作为模型蛋白的效率约为 70%，负载率可达 20%。Maltodextrin, dextrose equivalent 5.0-8.0 在 5 mg/mL 浓度下对细胞无毒，可用于药物递送系统。葡萄糖当量（DE）值反映了麦芽糊精的水解程度。DE 值越高，水解程度越高。Maltodextrin, dextrose equivalent 5.0-8.0 可形成稳定的纳米粒子，粒径范围为 170 nm 至 450 nm，粒径分布较窄^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(C₆H₁₀O₅)n·xH₂O

9050-36-6

固体

White to off-white

麦芽糊精,葡萄糖当量5.0-8.0

Room temperature in continental US; may vary elsewhere.

Store at room temperature, keep dry and cool

• [1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  [Content Brief]

  [2]. Takeiti, C. Y., et al. Morphological and Physicochemical Characterization of Commercial Maltodextrins with Different Degrees of Dextrose-Equivalent. International Journal of Food Properties, 13(2), 411–425.