1. Others JAK/STAT Signaling Stem Cell/Wnt Anti-infection
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  3. Niclosamide-13C6

Niclosamide-13C6  (Synonyms: 氯硝柳胺-13C6; BAY2353-13C6)

目录号: HY-B0497S1 纯度: ≥99.0%
COA 产品使用指南

Niclosamide-13C613C6 标记的 Niclosamide。Niclosamide (BAY2353) 是一种口服生物可利用的氯化水杨酰苯胺,具有驱虫和潜在的抗肿瘤活性。 Niclosamide (BAY2353) 可抑制 STAT3,在 HeLa 细胞中 IC50 0.25 μM,并在无细胞试验中抑制 DNA 复制。

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Niclosamide-<sup>13</sup>C<sub>6</sub> Chemical Structure

Niclosamide-13C6 Chemical Structure

CAS No. : 1325808-64-7

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1 mg ¥1909
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5 mg ¥4200
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10 mg ¥6800
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

333.08

Formula

C713C6H8Cl2N2O4

CAS 号
性状

固体

颜色

White to off-white

中文名称

氯硝柳胺-13C6; 杀螺胺-13C6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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