1. Membrane Transporter/Ion Channel
  2. EAAT
  3. (±)-threo-3-Methylglutamic acid

(±)-threo-3-Methylglutamic acid  (Synonyms: (+/-)-3--甲基谷氨酸)

目录号: HY-101227
产品使用指南

(±)-threo-3-Methylglutamic acid 是一种有效的 EAAT2/4 抑制剂。(±)-threo-3-Methylglutamic acid 也是一种离子型谷氨酸受体激动剂。(±)-threo-3-Methylglutamic acid 抑制杆外节对谷氨酸的摄取。

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(±)-threo-3-Methylglutamic acid Chemical Structure

(±)-threo-3-Methylglutamic acid Chemical Structure

CAS No. : 63088-04-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(±)-threo-3-Methylglutamic acid is a potent EAAT2/4 inhibitor. (±)-threo-3-Methylglutamic acid also is an ionotropic glutamate receptor agonist. (±)-threo-3-Methylglutamic acid inhibits glutamate uptake by rod outer segments[1][2].

IC50 & Target

EAAT2

 

EAAT4

 

体外研究
(In Vitro)

(±)-threo-3-Methylglutamic acid (0-300 µM) inhibits glutamate uptake by rod outer segments in a concentration-dependent manner with an IC50 value of 38.35 µM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

161.16

Formula

C6H11NO4

CAS 号
中文名称

(+/-)-3--甲基谷氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(±)-threo-3-Methylglutamic acid 相关分类

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产品名称:
(±)-threo-3-Methylglutamic acid
目录号:
HY-101227
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