Thrombospondin-2 蛋白, Human (HEK293, His)

THBS2 protein is an extracellular matrix protein involved in multiple biological processes, including cell adhesion, migration, and angiogenesis. It plays a vital role in tissue remodeling and wound healing. Thrombospondin-2 Protein, Human (HEK293, His) is the recombinant human-derived Thrombospondin-2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Thrombospondin-2 Protein, Human (HEK293, His) is 1154 a.a., with molecular weight of ~129.7 kDa.

THBS2 蛋白是一种粘附糖蛋白，在促进细胞与细胞以及细胞与基质相互作用方面发挥着至关重要的作用。这种同源三聚体蛋白质通过二硫键连接，并与各种分子相互作用以发挥其作用。具体来说，THBS2 通过其 TSP I 型重复序列与 CD36 相互作用，从而产生抗血管生成作用。此外，THBS2 还通过相同的重复序列与 HRG 相互作用，有效阻断 THBS2 与 CD36 的抗血管生成作用。此外，THBS2 能够结合纤维蛋白原、纤连蛋白、层粘连蛋白和 V 型胶原蛋白，进一步扩展其功能库。

Human

HEK293

C-10*His

P35442-1 (G19-I1172)

7058  [NCBI]

GHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFYEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI

Approximately 180-200 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

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  Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 with 10% trehalose as protectant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.