1. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  2. 5-HT Receptor Dopamine Receptor P-glycoprotein
  3. Risperidone-d6

Risperidone-d6  (Synonyms: 利培酮-d6; R 64 766-d6)

目录号: HY-11018S2
产品使用指南

Risperidone-d6 (R 64 766-d6) 是 Risperidone (HY-11018) 的氘代物。Risperidone是 5-HT2 受体的阻断剂,P-糖蛋白 (P-Glycoprotein) 的抑制剂 和 dopamine D2 受体的拮抗剂,其对 5-HT2A 和 dopamine D2 受体的 Ki 值分别为 4.8,5.9 nM。

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Risperidone-d<sub>6</sub> Chemical Structure

Risperidone-d6 Chemical Structure

CAS No. : 1225444-65-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Risperidone-d6 (R 64 766-d6) is the deuterium labeled Risperidone (HY-11018). Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively[1][2].

IC50 & Target[1][2]

D2 Receptor

5.9 nM (Ki)

5-HT2A Receptor

4.8 nM (Ki)

分子量

416.52

Formula

C23H21D6FN4O2

CAS 号
非标记 CAS

106266-06-2

中文名称

利培酮-d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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