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  3. RORγt Inverse agonist 3

RORγt Inverse agonist 3 

目录号: HY-128573
产品使用指南

RORγt Inverse agonist 3 是一种高效选择性的,有口服活性的视黄酸受体相关孤儿受体 RORγ 的逆向激动剂,对 hRORγ 和人类 IL-17 细胞 RORγt 作用的 EC50 值分别为 0.22 μM 和 0.15 μM。

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RORγt Inverse agonist 3 Chemical Structure

RORγt Inverse agonist 3 Chemical Structure

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Description

RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively[1].

IC50 & Target

EC50: 0.22 μM (hRORγ), 0.15 μM (RORγt, human IL-17 cells)[1]

Molecular Weight

616.56

Formula

C₂₉H₃₁Cl₂N₅O₄S

SMILES

CC(C)C1=NC2=C(C=CC=C2OCC3=C(Cl)C=CC(S(=O)(N4CCC[C@H]4C(NC)=O)=O)=C3Cl)C(C5=CN=CN5C)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
RORγt Inverse agonist 3
目录号:
HY-128573
需求量:

RORγt Inverse agonist 3

Cat. No.: HY-128573