2. Neuronal Signaling
  3. Amyloid-β
  4. RS-0406

RS-0406 是一种靶向 Amyloid-β 的 β-折叠破坏剂。RS-0406 能够抑制 Aβ(1-42) 的纤维生成，并保护原代海马神经元免受 Aβ(1-42) 诱导的细胞毒性。RS-0406 可用于神经系统疾病的研究，如阿尔茨海默病 (AD)。

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RS-0406

RS-0406 Chemical Structure

CAS No. : 530112-00-6

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RS-0406 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RS-0406 is a beta-sheet breaker targeting Amyloid-β. RS-0406 can inhibits Aβ(1-42) fibrillogenesis and protect against Aβ(1-42)-induced cytotoxicity in primary hippocampal neurons. RS-0406 can be used for the research of neurological disease, such as Alzheimer's disease (AD)[1].

体外研究
(In Vitro)

RS-0406 (10-100 μg/mL) 可抑制 25 μM Aβ(1-42) 的纤维生成，并能分解预先形成的 Aβ(1-42) 纤维[1]。
RS-0406 (10.3-3 μg/mL) 可改善 Aβ(1-42) 诱导的原代海马神经元毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RS-0406 相关抗体:
分子量

294.31

Formula

C16H14N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RS-0406 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RS-0406530112-00-6RS0406RS 0406Amyloid-ββ-amyloid peptideAβAbetaAβ(1-42)hippocampal neuronsAlzheimer's diseaseADInhibitorinhibitorinhibit

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目录号：
HY-114884
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