2. GPCR/G Protein
  3. G2A (GPR132)
  4. SB-583355

SB-583355 (Compound 56) 是一种有效的 G2A 拮抗剂。SB-583355 可通过 4-甲氧基苯基硼酸与 3-溴-4-羟基苯甲酸在特定条件下发生 Suzuki 反应，然后发生酰胺偶联反应来制备。SB-583355 可阻断在表达人 G2A 的 CHO-K1 细胞中由 9-HOPE 或 T-10148 介导的 G2A 活化。SB-583355 可用于研究炎症、髓系白血病和神经性疼痛。

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SB-583355

SB-583355 Chemical Structure

CAS No. : 3040121-49-8

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SB-583355 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain[1].

分子量

472.58

Formula

C29H32N2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SB-583355 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB-5833553040121-49-8SB583355SB 583355G2A (GPR132)Inhibitorinhibitorinhibit

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