2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. SCH 50911 hydrochloride

SCH 50911 hydrochloride，一种具有口服活性的选择竞争性 γ-氨基丁酸 B GABA(B)受体拮抗剂，与 GABA(B) 受体结合，IC50 为 1.1 μM。 SCH 50911 hydrochloride 拮抗 GABA(B) 自身受体，增加电刺激的 3H 溢出，IC50为 3 μM。

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SCH 50911 hydrochloride Chemical Structure

SCH 50911 hydrochloride Chemical Structure

CAS No. : 160415-07-6

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SCH 50911 hydrochloride 的其他形式现货产品:

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SCH 50911 hydrochloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

IC50 & Target

GABA(B)

1.1 μM (IC50)

分子量

209.67

Formula

C8H16ClNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SCH 50911 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH 50911160415-07-6SCH50911SCH-50911GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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