1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. SCH 50911 hydrochloride

SCH 50911 hydrochloride 

目录号: HY-12783
产品使用指南

SCH 50911 hydrochloride,一种具有口服活性的选择竞争性 γ-氨基丁酸 B GABA(B)受体拮抗剂,与 GABA(B) 受体结合,IC50 为 1.1 μM。 SCH 50911 hydrochloride 拮抗 GABA(B) 自身受体,增加电刺激的 3H 溢出,IC50为 3 μM。

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SCH 50911 hydrochloride Chemical Structure

SCH 50911 hydrochloride Chemical Structure

CAS No. : 160415-07-6

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Description

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

IC50 & Target

GABA(B)

1.1 μM (IC50)

Molecular Weight

209.67

Formula

C₈H₁₆ClNO₃

CAS No.

160415-07-6

SMILES

O=C(O)C[C@H]1CNC(C)(C)CO1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
SCH 50911 hydrochloride
目录号:
HY-12783
需求量:

SCH 50911 hydrochloride

Cat. No.: HY-12783